VTechWorks

VTechWorks provides global access to Virginia Tech scholarship, including journal articles, books, theses, dissertations, conference papers, slide presentations, technical reports, working papers, administrative documents, videos, images, and more by faculty, students, and staff. Faculty can deposit items to VTechWorks from Elements, including journal articles covered by the University open access policy. Email vtechworks@vt.edu for help.


 
Open Access Policy

Open Access Policy

Virginia Tech's open access policy enables researchers to deposit the accepted version of scholarly articles with no embargo.


Theses and Dissertations

Theses and Dissertations

Virginia Tech was first in the world to require ETDs in 1997, and continues to add scans of older theses and dissertations.


Open Textbooks

Open Textbooks

More than 50 freely available and openly licensed textbooks are among our most downloaded items.


Recent Submissions

Comparative Efficacy RCT of 3 Intensive Infant/Toddler Therapies for Unilateral Cerebral Palsy
DeLuca, Stephanie C.; Ramey, Sharon L.; Darragh, Amy R.; Conaway, Mark; Heathcock, Jill C.; Lo, Warren; Gordon, Andrew M.; Trucks, Mary Rebekah; Wallace, Dory; Cabral, Thais Invencao (American Academy of Pediatrics, 2026-02-01)
Objectives: Unilateral cerebral palsy (UCP) can result in lifelong upper extremity (UE) neuromotor impairment. While both constraint-induced movement therapy (CIMT) and bimanual training have demonstrated efficacy for children with UCP, there was limited evidence to inform treatment decision-making in children aged between 6 and 24 months. Thus, we performed a comparative efficacy trial testing 3 high-dose therapist-delivered interventions, 2 CIMT interventions varied by constraint type to bimanual/no-constraint intervention for use in treating this age group of children with UCP. Patients and Methods: Fifty-eight infants/toddlers with UCP diagnosis, aged 6 to 24 months, were enrolled and randomized. Exclusion criteria were uncontrolled seizures, fragile health, prior CIMT/bimanual therapy, and recent botulinum toxin. Participants were randomly assigned (1:1:1) to 1 of 3 treatments all delivered 3 hours/d and 5 days/wk for 4 weeks: CIMT/full-time cast, CIMT/part-time splint, or bimanual/no constraint. Anonymized assessments at baseline, end of treatment (EoT), and 6 months posttreatment included the Mini–Assisting Hand Assessment (AHA) for bimanual abilities and the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) Fine-Motor (FM) subscale on each UE for FM abilities. Results: Fifty-three infant/toddlers completed treatment and EoT assessment (mean age, 17.2 months), and 41 completed 6-month assessment. All groups had gains from intervention: Mini-AHA scores (P < .003) and Bayley-III FM/paretic side (P < .002). Bayley-III FM/nonparetic side also improved across groups (P < .001). The CIMT/full-time cast showed larger gains on Bayley-III FM/nonparetic side when compared with bimanual/no constraint (difference, 5.9; 95% CI, 1.2-10.5; P = .015). Conclusion: The trial confirms comparable benefits from therapist-delivered CIMT and bimanual/no-constraint interventions for infants/toddlers with UCP aged between 6 and 24 months.
Intellectual Property Committee: 2005-2006
(Virginia Tech, 2005-2006)
Intellectual Property Committee: September 22, 2020
(Virginia Tech, 2020-09-22)
Intellectual Property Committee: March 9, 2021
(Virginia Tech, 2021-03-09)
Intellectual Property Committee: February 17, 2016
(Virginia Tech, 2016-02-17)