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dc.contributor.authorDeshommes, Elise
dc.contributor.authorTardif, Robert
dc.contributor.authorEdwards, Marc
dc.contributor.authorSauvé, Sébastien
dc.contributor.authorPrévost, Michèle
dc.identifier.citationChemistry Central Journal. 2012 Nov 22;6(1):138
dc.description.abstractAbstract In vivo estimations of Pb particle bioavailability are costly and variable, because of the nature of animal assays. The most feasible alternative for increasing the number of investigations carried out on Pb particle bioavailability is in vitro testing. This testing method requires calibration using in vivo data on an adapted animal model, so that the results will be valid for childhood exposure assessment. Also, the test results must be reproducible within and between laboratories. The Relative Bioaccessibility Leaching Procedure, which is calibrated with in vivo data on soils, presents the highest degree of validation and simplicity. This method could be applied to Pb particles, including those in paint and dust, and those in drinking water systems, which although relevant, have been poorly investigated up to now for childhood exposure assessment.
dc.titleExperimental determination of the oral bioavailability and bioaccessibility of lead particles
dc.typeJournal Article
dc.description.versionPeer Reviewed
dc.rights.holderElise Deshommes et al.; licensee BioMed Central Ltd.

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  • BioMed Central [368]
    BioMed Central publications by Virginia Tech authors.

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