Now showing items 1-2 of 2
A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease
(Springer Nature, 2015-09-23)
We present a new molecular toolkit to investigate protein assemblies natively formed in the context of human disease. The system employs tunable microchips that can be decorated with switchable adaptor molecules to select ...
Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress
(Nature Publishing Group, 2017-03-06)
The precise manner in which physical changes to the breast cancer susceptibility protein (BRCA1) affect its role in DNA repair events remain unclear. Indeed, cancer cells harboring mutations in BRCA1 suffer from genomic ...