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Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress

Gilmore, Brian L.; Liang, Yanping; Winton, Carly E.; Patel, Kaya; Karageorge, Vasilea; Varano, A. Cameron; Dearnaley, Wwilliam; Sheng, Zhi; Kelly, Deborah F. (Nature Publishing Group, 2017-03-06)

The precise manner in which physical changes to the breast cancer susceptibility protein (BRCA1) affect its role in DNA repair events remain unclear. Indeed, cancer cells harboring mutations in BRCA1 suffer from genomic ...