Now showing items 1-6 of 6
A Numerical Investigation of the Electric and Thermal Cell Kill Distributions in Electroporation-Based Therapies in Tissue
Electroporation-based therapies are powerful biotechnological tools for enhancing the delivery of exogeneous agents or killing tissue with pulsed electric fields (PEFs). Electrochemotherapy (ECT) and gene therapy based on ...
Structural analysis of BRCA1 reveals modification hotspot
(Amer Assoc Advancement Science, 2017-09-01)
Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress
(Nature Publishing Group, 2017-03-06)
The precise manner in which physical changes to the breast cancer susceptibility protein (BRCA1) affect its role in DNA repair events remain unclear. Indeed, cancer cells harboring mutations in BRCA1 suffer from genomic ...
Enduring deficits in memory and neuronal pathology after blast-induced traumatic brain injury
(Nature Publishing Group, 2015-11-05)
Sex Differences in beta-Adrenergic Responsiveness of Action Potentials and Intracellular Calcium Handling in Isolated Rabbit Hearts
Cardioprotection in females, as observed in the setting of heart failure, has been attributed to sex differences in intracellular calcium handling and its modulation by b-adrenergic signaling. However, further studies ...
Bursts of Bipolar Microsecond Pulses Inhibit Tumor Growth
(Nature Publishing Group, 2015-10-13)
Irreversible electroporation (IRE) is an emerging focal therapy which is demonstrating utility in the treatment of unresectable tumors where thermal ablation techniques are contraindicated. IRE uses ultra-short duration, ...