Now showing items 1-10 of 10
Discovering Networks of Perturbed Biological Processes in Hepatocyte Cultures
The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs and environmental ...
ICTAS Connection, May 2011
(Virginia Tech, 2011-05)
This newsletter details new developments in staff and programs for ICTAS. In this issue: Nanoscale science and engineering. Also, doctoral scholar poster session and ICTAS II grand opening.
ICTAS at NCR: VT-Serge meeting
(Institute for Critical Technology and Applied Science (ICTAS), Virginia Tech, 2011-05-04)
Renewable Hydrogen Carrier — Carbohydrate: Constructing the Carbon-Neutral Carbohydrate Economy
The hydrogen economy presents an appealing energy future but its implementation must solve numerous problems ranging from low-cost sustainable production, high-density storage, costly infrastructure, to eliminating safety concern. The use of renewable carbohydrate as a high-density hydrogen carrier and energy source for hydrogen production is possible due to emerging cell-free synthetic biology technology—cell-free synthetic pathway biotransformation (SyPaB). Assembly of numerous enzymes and co-enzymes in vitro can create complicated set of biological reactions or pathways that microorganisms or catalysts cannot complete, for example, C<sub>6</sub>H<sub>10</sub>O<sub>5</sub> (aq) + 7 H<sub>2</sub>O (l) à 12 H<sub>2</sub> (g) + 6 CO<sub>2</sub> (g) (PLoS One 2007, 2:e456). Thanks to 100% selectivity of enzymes, modest reaction conditions, and high-purity of generated hydrogen, carbohydrate is a promising hydrogen carrier for end users. Gravimetric density of carbohydrate is 14.8 H<sub>2</sub> mass% if water can be recycled from proton exchange membrane fuel cells or 8.33% H<sub>2</sub> mass% without water recycling. Renewable carbohydrate can be isolated from plant biomass or would be produced from a combination of solar electricity/hydrogen and carbon dioxide fixation mediated by high-efficiency artificial photosynthesis mediated by SyPaB. The construction of this carbon-neutral carbohydrate economy would address numerous sustainability challenges, such as electricity and hydrogen storage, CO<sub>2</sub> fixation and long-term storage, water conservation, transportation fuel production, plus feed and food production....
Seamless Integration of Technology & Society for a Sustainable Future
(Institute for Critical Technology and Applied Science (ICTAS), Virginia Tech, 2011-02-16)
Recognition Luncheon for American Electric Power Foundation and Mr. Joseph H. Vipperman, Jr.
(Institute for Critical Technology and Applied Science (ICTAS), Virginia Tech, 2011-05-03)
Network-based functional enrichment
Background Many methods have been developed to infer and reason about molecular interaction networks. These approaches often yield networks with hundreds or thousands of nodes and up to an order of magnitude more edges. ...
The Black Swan(s) & Transformative Technologies at Dahlgren: An informal discussion of the future
(Institute for Critical Technology and Applied Science (ICTAS), Virginia Tech, 2011-09-16)
Energy Initiatives at Virginia Tech - A Snapshot
(Institute for Critical Technology and Applied Science (ICTAS), Virginia Tech, 2011-10-06)
Energy Efficiency Analysis: Biomass-to-Wheel Efficiency Related with Biofuels Production, Fuel Distribution, and Powertrain Systems
Background Energy efficiency analysis for different biomass-utilization scenarios would help make more informed decisions for developing future biomass-based transportation systems. Diverse biofuels produced from biomass ...