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  • Physical Measures to Reduce Exposure to Tap Water-Associated Nontuberculous Mycobacteria 

    Norton, Grant J.; Williams, Myra; Falkinham, Joseph O., III; Honda, Jennifer R. (2020-06-12)
    Nontuberculous mycobacteria (NTM) that cause human disease can be isolated from household tap water. Easy-to-use physical methods to reduce NTM from this potential source of exposure are needed. Filters and UV disinfection ...
  • Magnetic alignment enhances homing efficiency of hunting dogs 

    Benediktova, Katerina; Adamkova, Jana; Svoboda, Jan; Painter, Michael Scott; Bartos, Ludek; Novakova, Petra; Vynikalova, Lucie; Hart, Vlastimil; Phillips, John; Burda, Hynek (2020-06-16)
    Despite anecdotal reports of the astonishing homing abilities in dogs, their homing strategies are not fully understood. We equipped 27 hunting dogs with GPS collars and action cams, let them freely roam in forested areas, ...
  • Backbone Interactions Between Transcriptional Activator ExsA and Anti-Activator ExsD Facilitate Regulation of the Type III Secretion System in Pseudomonas aeruginosa 

    Shrestha, Manisha; Bernhards, Robert C.; Fu, Yichen; Ryan, Kylie; Schubot, Florian D. (2020-06-18)
    The type III secretion system (T3SS) is a pivotal virulence mechanism of many Gram-negative bacteria. During infection, the syringe-like T3SS injects cytotoxic proteins directly into the eukaryotic host cell cytoplasm. In ...
  • Diversity and function of terpene synthases in the production of carrot aroma and flavor compounds 

    Muchlinski, Andrew; Ibdah, Mwafaq; Ellison, Shelby; Yahyaa, Mossab; Nawade, Bhagwat; Laliberte, Suzanne; Senalik, Douglas; Simon, Philipp; Whitehead, Susan R.; Tholl, Dorothea (2020-06-19)
    Carrot (Daucus carota L.) is an important root vegetable crop with high nutritional value, characteristic flavor, and benefits to human health. D. carota tissues produce an essential oil that is rich in volatile terpenes ...
  • Asymmetric clustering of centrosomes defines the early evolution of tetraploid cells 

    Baudoin, Nicolaas C.; Nicholson, Joshua M.; Soto, Kimberly; Martin, Olga; Chen, Jing; Cimini, Daniela (eLife Sciences Publications, 2020-04-29)
    Tetraploidy has long been of interest to both cell and cancer biologists, partly because of its documented role in tumorigenesis. A common model proposes that the extra centrosomes that are typically acquired during ...
  • A simplified field protocol for genetic sampling of birds using buccal swabs 

    Vilstrup, Julia T.; Mullins, Thomas D.; Miller, Mark P.; McDearman, Will; Walters, Jeffrey R.; Haig, Susan M. (2018-03)
    DNA sampling is an essential prerequisite for conducting population genetic studies. For many years, blood sampling has been the preferred method for obtaining DNA in birds because of their nucleated red blood cells. ...
  • Patterns of Circulating Corticosterone in a Population of Rattlesnakes Afflicted with Snake Fungal Disease: Stress Hormones as a Potential Mediator of Seasonal Cycles in Disease Severity and Outcomes 

    Lind, Craig; Moore, Ignacio T.; Akcay, Caglar; Vernasco, Ben J.; Lorch, Jeffrey M.; Farrell, Terence M. (2018-03)
    Snake fungal disease (SFD) is an emerging threat to snake populations in the United States. Fungal pathogens are often associated with a physiological stress response mediated by the hypothalamo-pituitary-adrenal axis ...
  • A multi-lake comparative analysis of the General Lake Model (GLM): Stress-testing across a global observatory network 

    Bruce, Louise C.; Frassl, Marieke A.; Arhonditsis, George B.; Gal, Gideon; Hamilton, David P.; Hanson, Paul C.; Hetherington, Amy L.; Melack, John M.; Read, Jordan S.; Rinke, Karsten; Rigosi, Anna; Trolle, Dennis; Winslow, Luke; Adrian, Rita; Ayala, Ana I.; Bocaniov, Serghei A.; Boehrer, Bertram; Boon, Casper; Brookes, Justin D.; Bueche, Thomas; Busch, Brendan D.; Copetti, Diego; Cortes, Alicia; de Eyto, Elvira; Elliott, J. Alex; Gallina, Nicole; Gilboa, Yael; Guyennon, Nicolas; Huang, Lei; Kerimoglu, Onur; Lenters, John D.; MacIntyre, Sally; Makler-Pick, Vardit; McBride, Chris G.; Moreira, Santiago; Oezkundakci, Deniz; Pilotti, Marco; Rueda, Francisco J.; Rusak, James A.; Samal, Nihar R.; Schmid, Martin; Shatwell, Tom; Snorthheim, Craig; Soulignac, Frederic; Valerio, Giulia; van der Linden, Leon; Vetter, Mark; Vincon-Leite, Brigitte; Wang, Junbo; Weber, Michael; Wickramaratne, Chaturangi; Woolway, R. Iestyn; Yao, Huaxia; Hipsey, Matthew R. (2018-04)
    The modelling community has identified challenges for the integration and assessment of lake models due to the diversity of modelling approaches and lakes. In this study, we develop and assess a one-dimensional lake model ...
  • Continental-scale decrease in net primary productivity in streams due to climate warming 

    Song, Chao; Dodds, Walter K.; Ruegg, Janine; Argerich, Alba; Baker, Christina L.; Bowden, William B.; Douglas, Michael M.; Farrell, Kaitlin J.; Flinn, Michael B.; Garcia, Erica A.; Helton, Ashley M.; Harms, Tamara K.; Jia, Shufang; Jones, Jeremy B.; Koenig, Lauren E.; Kominoski, John S.; McDowell, William H.; McMaster, Damien; Parker, Samuel P.; Rosemond, Amy D.; Ruffing, Claire M.; Sheehan, Ken R.; Trentman, Matt T.; Whiles, Matt R.; Wollheim, Wilfred M.; Ballantyne, Ford (2018-06)
    Streams play a key role in the global carbon cycle. The balance between carbon intake through photosynthesis and carbon release via respiration influences carbon emissions from streams and depends on temperature. However, ...
  • Experimental logging alters the abundance and community composition of ovipositing mosquitoes in the southern Appalachians 

    Hopkins, M. Camille; Thomason, Courtney A.; Brown, Bryan L.; Kirkpatrick, Laila T.; Paulson, Sally L.; Hawley, Dana M. (2018-08)
    1. The loss of intact forest via logging can influence vector-borne disease dynamics in part by altering the abundance or diversity of mosquito species. Using an experimental field approach, we characterised how two types ...
  • Utilization of Multiparametric MRI of Prostate in Patients under Consideration for or Already in Active Surveillance: Correlation with Imaging Guided Target Biopsy 

    Yu, Jinxing; Fulcher, Ann S.; Winks, Sarah; Turner, Mary A.; Behl, William; Ware, Anna Lee; Mukhopadhyay, Nitai D.; Kim, Candice; Jackson, Christopher; Bajaj, Harnek S.; Hampton, Lance J. (MDPI, 2020-06-29)
    This study sought to assess the value of multiparametric magnetic resonance image (mp-MRI) in patients with a prostate cancer (PCa) Gleason score of 6 or less under consideration for or already in active surveillance and ...
  • Effect of Washing, Waxing and Low-Temperature Storage on the Postharvest Microbiome of Apple 

    Abdelfattah, Ahmed; Whitehead, Susan R.; Macarisin, Dumitru; Liu, Jia; Burchard, Erik; Freilich, Shiri; Dardick, Christopher; Droby, Samir; Wisniewski, Michael (MDPI, 2020-06-23)
    There is growing recognition of the role that the microbiome plays in the health and physiology of many plant species. However, considerably less research has been conducted on the postharvest microbiome of produce and the ...
  • Seasonal sex steroids indicate reproductive costs associated with snake fungal disease 

    Lind, C. M.; Lorch, J. M.; Moore, I. T.; Vernasco, B. J.; Farrell, T. M. (2019-02)
    Emergent diseases may result in population declines by inducing mortality directly or through sublethal effects on host reproduction. Snake fungal disease (SFD) is an emerging threat to biodiversity, but the sublethal ...
  • Changes in genetic diversity and differentiation in Red-cockaded woodpeckers (Dryobates borealis) over the past century 

    Miller, Mark P.; Vilstrup, Julia T.; Mullins, Thomas D.; McDearman, Will; Walters, Jeffrey R.; Haig, Susan M. (2019-05)
    Red-cockaded woodpeckers (RCW; Dryobates borealis) declined after human activities reduced their fire-maintained pine ecosystem to <3% of its historical range in the southeastern United States and degraded remaining habitat. ...
  • Diverse GABAergic neurons organize into subtype-specific sublaminae in the ventral lateral geniculate nucleus 

    Sabbagh, Ubadah; Govindaiah, Gubbi; Somaiya, Rachana D.; Ha, Ryan V.; Wei, Jessica C.; Guido, William; Fox, Michael A. (Wiley, 2020-05-19)
    In the visual system, retinal axons convey visual information from the outside world to dozens of distinct retinorecipient brain regions and organize that information at several levels, including either at the level of ...
  • Effects of low-density urbanization on genetic structure in the Song Sparrow 

    Brewer, Valerie N.; Lane, Samuel J.; Sewall, Kendra B.; Mabry, Karen E. (PLoS, 2020-06-12)
    Urbanization fragments landscapes and can impede the movement of organisms through their environment, which can decrease population connectivity. Reduction in connectivity influences gene flow and allele frequencies, and ...
  • Sex linkage of the skeletal muscle sodium channel gene (SCN4A) explains apparent deviations from Hardy–Weinberg equilibrium of tetrodotoxin-resistance alleles in garter snakes (Thamnophis sirtalis) 

    Gendreau, Kerry L.; Hague, Michael T. J.; Feldman, Chris R.; Brodie, Edmund D., Jr.; Brodie, Edmund D., III; McGlothlin, Joel W. (Springer Nature, 2020-02-28)
    The arms race between tetrodotoxin-bearing Pacific newts (Taricha) and their garter snake predators (Thamnophis) in western North America has become a classic example of coevolution, shedding light on predator-prey dynamics, ...
  • Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission 

    Wood, Chelsea L.; Sokolow, Susanne H.; Jones, Isabel J.; Chamberlin, Andrew J.; Lafferty, Kevin D.; Kuris, Armand M.; Jocque, Merlijn; Hopkins, Skylar; Adams, Grant; Buck, Julia C.; Lund, Andrea J.; Garcia-Vedrenne, Ana E.; Fiorenza, Evan; Rohr, Jason R.; Allan, Fiona; Webster, Bonnie; Rabone, Muriel; Webster, Joanne P.; Bandagny, Lydie; Ndione, Raphael; Senghor, Simon; Schacht, Anne-Marie; Jouanard, Nicolas; Riveau, Gilles; De Leo, Giulio A. (2019-11-12)
    Recently, the World Health Organization recognized that efforts to interrupt schistosomiasis transmission through mass drug administration have been ineffective in some regions; one of their new recommended strategies for ...
  • Zero or not? Causes and consequences of zero-flow stream gage readings 

    Zimmer, Margaret A.; Kaiser, Kendra E.; Blaszczak, Joanna R.; Zipper, Samuel C.; Hammond, John C.; Fritz, Ken M.; Costigan, Katie H.; Hosen, Jacob; Godsey, Sarah E.; Allen, George H.; Kampf, Stephanie; Burrows, Ryan M.; Krabbenhoft, Corey A.; Dodds, Walter; Hale, Rebecca; Olden, Julian D.; Shanafield, Margaret; DelVecchia, Amanda G.; Ward, Adam S.; Mims, Meryl C.; Datry, Thibault; Bogan, Michael T.; Boersma, Kate S.; Busch, Michelle H.; Jones, C. Nathan; Burgin, Amy J.; Allen, Daniel C. (2020-05)
    Streamflow observations can be used to understand, predict, and contextualize hydrologic, ecological, and biogeochemical processes and conditions in streams. Stream gages are point measurements along rivers where streamflow ...
  • Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus 

    Dakhama, Azzeddine; Al Mubarak, Reem; Pavelka, Nicole; Voelker, Dennis; Seibold, Max; Ledford, Julie G.; Kraft, Monica; Li, Liwu; Chu, Hong Wei (2020-01)
    The negative immune regulator Tollip inhibits the proinflammatory response to rhinovirus (RV) infection, a contributor to airway neutrophilic inflammation and asthma exacerbations, but the underlying molecular mechanisms ...

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