Scholarly Works, Department of Biomedical Engineering and Mechanics
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Research articles, presentations, and other scholarship
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Sub-second Dopamine and Serotonin Signaling in Human Striatum during Perceptual Decision-Making
(CellPress, 2020-12-09)Recent animal research indicates that dopamine and serotonin, neuromodulators traditionally linked to appetitive and aversive processes, are also involved in sensory inference and decisions based on such inference. We ... -
Physical Performance Improves With Time and a Functional Knee Brace in Athletes After ACL Reconstruction
(2020-08)Background: Athletes who return to sport (RTS) after anterior cruciate ligament reconstruction (ACLR) often have reduced physical performance and a high reinjury rate. Additionally, it is currently unclear how physical ... -
Validity of flexicurve and motion capture for measurements of thoracic kyphosis vs standing radiographic measurements
(2020-08)Thoracic kyphosis varies among healthy adults and typically increases with age. Excessive kyphosis (hyperkyphosis) is associated with negative health. Spinal alignment also affects spine loading, with implications for ... -
Raman chemometric urinalysis (Rametrix) as a screen for bladder cancer
(2020-08-21)Bladder cancer (BCA) is relatively common and potentially recurrent/progressive disease. It is also costly to detect, treat, and control. Definitive diagnosis is made by examination of urine sediment, imaging, direct ... -
Plasma Biomarker Concentrations Associated With Return to Sport Following Sport-Related Concussion in Collegiate Athletes-A Concussion Assessment, Research, and Education (CARE) Consortium Study
(2020-08-27)Question Are plasma biomarkers associated with a return-to-sport period of less than 14 days vs 14 days or more in male and female collegiate athletes following a sport-related concussion? Findings This diagnostic study, ... -
Biomarkers in Sports and Exercise: Tracking Health, Performance, and Recovery in Athletes
(Wolters Kluwer Health, Inc., 2017)Biomarker discovery and validation is a critical aim of the medical and scientific community. Research into exercise and diet-related biomarkers aims to improve health, performance, and recovery in military personnel, ... -
Augmentation of brain tumor interstitial flow via focused ultrasound promotes brain-penetrating nanoparticle dispersion and transfection
(2020-04)The delivery of systemically administered gene therapies to brain tumors is exceptionally difficult because of the blood-brain barrier (BBB) and blood-tumor barrier (BTB). In addition, the adhesive and nanoporous tumor ... -
Mass Transport and Turbulent Statistics within Two Branching Coral Colonies
(MDPI, 2020-09-04)Large eddy simulations were performed to characterize the flow and mass transport mechanisms in the interior of two Pocillopora coral colonies with different geometries, one with a relatively loosely branched ... -
The role of the gap junction perinexus in cardiac conduction: Potential as a novel anti-arrhythmic drug target
(Elsevier, 2018-09-19)Cardiovascular disease remains the single largest cause of natural death in the United States, with a significant cause of mortality associated with cardiac arrhythmias. Presently, options for treating and preventing ... -
Passive water ascent in a tall, scalable synthetic tree
(Nature Research, 2020)The transpiration cycle in trees is powered by a negative water potential generated within the leaves, which pumps water up a dense array of xylem conduits. Synthetic trees can mimic this transpiration cycle, but have been ... -
Development of a Multi-Pulse Conductivity Model for Liver Tissue Treated With Pulsed Electric Fields
(2020-05-19)Pulsed electric field treatment modalities typically utilize multiple pulses to permeabilize biological tissue. This electroporation process induces conductivity changes in the tissue, which are indicative of the extent ... -
Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing
(2020-05-22)New methods of tumor ablation have shown exciting efficacy in pre-clinical models but often demonstrate limited success in the clinic. Due to a lack of quality or quantity in primary malignant tissue specimens, therapeutic ... -
Exploring optimization strategies for improving explicit water models: Rigid n-point model and polarizable model based on Drude oscillator
(PLOS, 2019-11-14)Rigid n-point water models are widely used in atomistic simulations, but have known accuracy drawbacks. Increasing the number of point charges, as well as adding electronic polarizability, are two common strategies for ... -
Perturbation-based balance training targeting both slip- and trip-induced falls among older adults: a randomized controlled trial
(2020-06-12)Abstract Background Falls are the leading cause of injuries among older adults. Perturbation-based balance training (PBT) is an innovative approach to fall prevention that aims to improve the reactive balance response ... -
The Rametrix (TM) PRO Toolbox v1.0 for MATLAB (R)
(2020-01-06)Background. Existing tools for chemometric analysis of vibrational spectroscopy data have enabled characterization of materials and biologicals by their broad molecular composition. The Rametrix (TM) LITE Toolbox v1.0 for ... -
Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium
(2020-01-24)Question Is sport-related concussion associated with levels of traumatic brain injury biomarkers in collegiate athletes? Findings In this case-control study of 504 collegiate athletes with concussion, contact sport control ... -
Adding four-dimensional data assimilation by analysis nudging to the Model for Prediction Across Scales – Atmosphere
(Copernicus Publications, 2018-07-16)The Model for Prediction Across Scales – Atmosphere (MPAS-A) has been modified to allow fourdimensional data assimilation (FDDA) by the nudging of temperature, humidity, and wind toward target values predefined on the ... -
Improving the simulation of convective dust storms in regional-to-global models
(AGU Publications, 2017-09-05)Convective dust storms have significant impacts on atmospheric conditions and air quality and are a major source of dust uplift in summertime. However, regional-to-global models generally do not accurately simulate these ... -
Cytoskeletal Disruption after Electroporation and Its Significance to Pulsed Electric Field Therapies
(MDPI, 2020-04-30)Pulsed electric fields (PEFs) have become clinically important through the success of Irreversible Electroporation (IRE), Electrochemotherapy (ECT), and nanosecond PEFs (nsPEFs) for the treatment of tumors. PEFs increase ... -
Spinal Compressive Forces in Adolescent Idiopathic Scoliosis With and Without Carrying Loads: A Musculoskeletal Modeling Study
(2020-03-03)The pathomechanisms of curve progression in adolescent idiopathic scoliosis (AIS) remain poorly understood and biomechanical data are limited. A deeper insight into spinal loading could provide valuable information toward ...
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