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  Bile duct obstruction associated with pancreatitis in 46 dogs 

  Wilkinson, Ashley R.; DeMonaco, Stefanie M.; Panciera, David L.; Otoni, Cristiane C.; Leib, Michael S.; Larson, Martha M. (Wiley, 2020)

  Background: Pancreatitis is a common cause of extrahepatic bile duct obstruction (EHBDO) in dogs. Information describing the clinical course of dogs with pancreatitis associated bile duct obstruction (PABDO) is limited. ...
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  Comparison of direct measurement of intracranial pressures and presumptive clinical and magnetic resonance imaging indicators of intracranial hypertension in dogs with brain tumors 

  Giannasi, Savannah; Kani, Yukitaka; Hsu, Fang-Chi; Rossmeisl, John H. (2020-05-16)

  Background Intracranial hypertension (ICH) is often presumptively diagnosed based on clinical or imaging findings. Clinical or imaging surrogates of ICH are not usually validated with reference standard direct intracranial ...
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  Measurement of preprandial and postprandial urine calcium to creatinine ratios in male Miniature Schnauzers with and without urolithiasis 

  Carr, Susan V.; Grant, David C.; DeMonaco, Stefanie M.; Shepherd, Megan (2020-03)

  Background We aimed to identify a simple test for excessive calciuresis and predict calcium oxalate (CaOx) disease in Miniature Schnauzers. We investigated the impact of postprandial time on the urine calcium to creatinine ...
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  Echocardiographic and electrocardiographic evaluation of North American Irish Wolfhounds 

  Tyrrell, William D., Jr.; Abbott, Jonathan A.; Rosenthal, Steven L.; Dentino, Mariellen; Abrams, Frances (2020-03)

  Background Cardiac disease is an important cause of morbidity and mortality in Irish Wolfhounds (IWs), but its prevalence and clinical characteristics in North American IWs are incompletely described. Hypothesis/Objectives ...
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  Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study 

  Boswood, Adrian; Gordon, Sonya G.; Haggstrom, Jens; Vanselow, Martin; Wess, Gerhard; Stepien, Rebecca L.; Oyama, Mark A.; Keene, Bruce W.; Bonagura, John; MacDonald, Kristin A.; Patteson, Mark; Smith, Sarah; Fox, Philip R.; Sanderson, Karen; Woolley, Richard; Szatmari, Viktor; Menaut, Pierre; Church, Whitney M.; O'Sullivan, M. Lynne; Jaudon, Jean-Philippe; Kresken, Jan-Gerd; Rush, John; Barrett, Kirstie A.; Rosenthal, Steven L.; Saunders, Ashley B.; Ljungvall, Ingrid; Deinert, Michael; Bomassi, Eric; Estrada, Amara H.; Fernandez Del Palacio, Maria J.; Moise, N. Sydney; Abbott, Jonathan A.; Fujii, Yoko; Spier, Alan; Luethy, Michael W.; Santilli, Roberto A.; Uechi, Masami; Tidholm, Anna; Schummer, Christoph; Watson, Philip (2020-02)

  Background The Evaluation of pimobendan in dogs with cardiomegaly caused by preclinical myxomatous mitral valve disease (EPIC) study monitored dogs with myxomatous mitral valve disease (MMVD) as they developed congestive ...
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  Temporal Characterization of Blood–Brain Barrier Disruption with High-Frequency Electroporation 

  Lorenzo, Melvin F.; Thomas, Sean C.; Kani, Yukitaka; Hinckley, Jonathan; Lee, Matthew; Adler, Joy; Verbridge, Scott; Hsu, Fang-Chi; Robertson, John L.; Davalos, Rafael V.; Rossmeisl, John H. (MDPI, 2019-11-23)

  Treatment of intracranial disorders suffers from the inability to accumulate therapeutic drug concentrations due to protection from the blood–brain barrier (BBB). Electroporation-based therapies have demonstrated the ...
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  High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity 

  Ringel-Scaia, Veronica M.; Beitel-White, Natalie; Lorenzo, Melvin F.; Brock, Rebecca M.; Huie, Kathleen E.; Coutermarsh-Ott, Sheryl; Eden, Kristin; McDaniel, Dylan K.; Verbridge, Scott; Rossmeisl, John H., Jr.; Oestreich, Kenneth J.; Davalos, Rafael, V.; Allen, Irving C. (2019-06)

  Background: Despite promising treatments for breast cancer, mortality rates remain high and treatments for metastatic disease are limited. High-frequency irreversible electroporation (H-FIRE) is a novel tumor ablation ...
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  Canine Snake-Eye Myelopathy: Clinical, Magnetic Resonance Imaging, and Pathologic Findings in Four Cases 

  Rossmeisl, John H., Jr.; Cecere, Thomas E.; Kortz, Gregg D.; Geiger, David A.; Shinn, Richard L.; Hinckley, Jonathan; Caudell, David L.; Stahle, Jessica A. (Frontiers, 2019-07-05)

  Intramedullary signal change (ISC) is a non-specific finding that is frequently observed on magnetic resonance imaging (MRI) examinations of the canine spinal cord. ISC can represent a variety of primary pathological ...
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  Prevalence and Prognostic Importance of Pulmonary Hypertension in Dogs with Myxomatous Mitral Valve Disease 

  Borgarelli, Michele; Abbott, J.; Braz-Ruivo, L.; Chiavegato, D.; Crosara, S.; Lamb, K.; Ljungvall, I.; Poggi, M.; Santilli, R. A.; Haggstrom, J. (American College of Veterinary Internal Medicine, 2015-03)

  BackgroundPulmonary hypertension (PH) is common in dogs with myxomatous mitral valve disease (MMVD) but its effect on clinical outcome has not been investigated. Hypothesis/objectivesThe presence of PH worsens the outcome ...
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  Histopathologic Variation between Liver Lobes in Dogs 

  Kemp, S. D.; Zimmerman, K. L.; Panciera, D. L.; Monroe, W. E.; Leib, M. S. (American College of Veterinary Internal Medicine, 2015-01)

  Background: Biopsy of the liver evaluates a small portion of tissue, with inferences made to the entire organ. The method and number of biopsies obtained are tempered by consideration of the risks and benefits. Recommendations ...
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  A Comparison of Liver Sampling Techniques in Dogs 

  Kemp, S. D.; Zimmerman, K. L.; Panciera, D. L.; Monroe, W. E.; Leib, M. S.; Lanz, Otto I. (American College of Veterinary Internal Medicine, 2015-01)

  Background: The liver sampling technique in dogs that consistently provides samples adequate for accurate histopathologic interpretation is not known. Hypothesis/ Objectives: To compare histopathologic results of liver ...
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  Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial 

  Boswood, A.; Haggstrom, J.; Gordon, S. G.; Wess, G.; Stepien, R. L.; Oyama, M. A.; Keene, B. W.; Bonagura, J.; MacDonald, K. A.; Patteson, M.; Smith, S.; Fox, P. R.; Sanderson, K.; Woolley, R.; Szatmari, V.; Menaut, P.; Church, W. M.; O'Sullivan, M. L.; Jaudon, J-P; Kresken, J-G; Rush, J.; Barrett, K. A.; Rosenthal, S. L.; Saunders, A. B.; Ljungvall, I.; Deinert, M.; Bomassi, E.; Estrada, A. H.; Fernandez Del Palacio, M. J.; Moise, N. S.; Abbott, J. A.; Fujii, Y.; Spier, A.; Luethy, M. W.; Santilli, R. A.; Uechi, M.; Tidholm, A.; Watson, P. (American College of Veterinary Internal Medicine, 2016-11)

  Background: Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on dogs before the onset of CHF is unknown. Hypothesis/Objectives: ...
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  Utility of Tissue Doppler Imaging in the Echocardiographic Evaluation of Left and Right Ventricular Function in Dogs with Myxomatous Mitral Valve Disease with or without Pulmonary Hypertension 

  Toaldo, M. Baron; Poser, H.; Menciotti, Giulio; Battaia, S.; Contiero, B.; Cipone, M.; Diana, A.; Mazzotta, E.; Guglielmini, C. (American College of Veterinary Internal Medicine, 2016-05)

  Background: In human medicine, right ventricular (RV) functional parameters represent a tool for risk stratification in patients with congestive heart failure caused by left heart disease. Little is known about RV alterations ...
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  Spontaneous Course of Biliary Sludge Over 12 Months in Dogs with Ultrasonographically Identified Biliary Sludge 

  DeMonaco, S. M.; Grant, David C.; Larson, M. M.; Panciera, D. L.; Leib, M. S. (American College of Veterinary Internal Medicine, 2016-05)

  Background: Biliary sludge is associated with gallbladder (GB) dysmotility and mucus hypersecretion suggesting a link between biliary sludge, and the formation of GB mucoceles (GMT). If biliary sludge progresses to GBM, ...
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  Red Blood Cell Distribution Width, Hematology, and Serum Biochemistry in Dogs with Echocardiographically Estimated Precapillary and Postcapillary Pulmonary Arterial Hypertension 

  Mazzotta, E.; Guglielmini, C.; Menciotti, Giulio; Contiero, B.; BaronToaldo, M.; Berlanda, M.; Poser, H. (American College of Veterinary Internal Medicine, 2016-11)

  Background: Red blood cell distribution width (RDW) is a quantitative measurement of anisocytosis. RDW has prognostic value in humans with different cardiovascular and systemic disorders, but few studies have investigated ...
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  Measurement Variation and Repeatability of Echocardiographic Variables Used to Estimate Pulmonary Artery Pressure in Dogs 

  Abbott, J. A.; Gentile-Solomon, J. M. (American College of Veterinary Internal Medicine, 2017-11)

  Background: Pulmonary hypertension (PH) is an important clinical entity in dogs. Pulmonary hypertension is generally identified based on echocardiographic findings, but measurement variation of the variables most often ...
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  ACVIM small animal consensus statement on safe use of cytotoxic chemotherapeutics in veterinary practice 

  Smith, Annette N.; Klahn, Shawna; Phillips, Brenda; Parshley, Lisa; Bennett, Peter; Flory, Andi; Calderon, Rosemary (American College of Veterinary Internal Medicine, 2018-05)

  The purpose of this report is to offer a consensus opinion of ACVIM oncology diplomates and technicians on the safe use of cytotoxic chemotherapeutics in veterinary practice. The focus is on minimizing harm to the personnel ...
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  Diagnostic accuracy of stereotactic brain biopsy for intracranial neoplasia in dogs: Comparison of biopsy, surgical resection, and necropsy specimens 

  Kani, Yukitaka; Cecere, Thomas E.; Lahmers, Kevin K.; LeRoith, Tanya; Zimmerman, Kurt L.; Isom, Scott; Hsu, Fang-Chi; Debinksi, Waldemar; Robertson, John L.; Rossmeisl, John H. (American College of Veterinary Internal Medicine, 2019-05)

  Background Stereotactic brain biopsy (SBB) is a technique that allows for definitive diagnosis of brain lesions. Little information is available regarding the diagnostic utility of SBB in dogs with intracranial diseases. ...
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  Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study 

  Boswood, A.; Gordon, S. G.; Haggstrom, J.; Wess, G.; Stepien, R. L.; Oyama, M. A.; Keene, B. W.; Bonagura, J.; MacDonald, K. A.; Patteson, M.; Smith, S.; Fox, P. R.; Sanderson, K.; Woolley, R.; Szatmari, V.; Menaut, P.; Church, W. M.; O'Sullivan, M. L.; Jaudon, J. -P.; Kresken, J. -G.; Rush, J.; Barrett, K. A.; Rosenthal, S. L.; Saunders, A. B.; Ljungvall, I.; Deinert, M.; Bomassi, E.; Estrada, A. H.; Fernandez Del Palacio, M. J.; Moise, N. S.; Abbott, J. A.; Fujii, Y.; Spier, A.; Luethy, M. W.; Santilli, R. A.; Uechi, M.; Tidholm, A.; Schummer, C.; Watson, P. (American College of Veterinary Internal Medicine, 2018-01)

  Background: Changes in clinical variables associated with the administration of pimobendan to dogs with preclinical myxomatous mitral valve disease (MMVD) and cardiomegaly have not been described. Objectives: To investigate ...
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  A Case of Segmental Aplasia of the Uterus, Cervix, and Cranial Vagina in a Cat 

  Souther, Samantha; Baik, Nam Joo; Clapp, Kemba; Nappier, Mike; Sponenberg, D. Phillip; Cecere, Julie (Frontiers, 2019-05-15)

  This case documents a rare set of congenital anomalies that resulted in an atypical cystic lesion in the cranial vagina of a queen. A discrete cystic lesion was identified in an 8 year old intact female domestic shorthair ...

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