Browsing Fralin Life Sciences Institute by Issue Date
Now showing items 1-20 of 560
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Method for the conversion of cephalomannine to taxol and for the preparation of n-acyl analogs of taxol
(United States Patent and Trademark Office, 1995-11-28)The natural product cephalomannine can be converted to the important anticancer natural product taxol by a simple process involving the steps of dihydroxylation to give cephalomannine-diols, diol cleavage, benzoylation at ... -
2002 Annual Report
(Virginia Bioinformatics Institute, 2002-11-03) -
Virginia Bioinformatics Institute 2003 Annual Report
(Virginia Bioinformatics Institute, 2004-01-18) -
Reproducibility, bioinformatic analysis and power of the SAGE method to evaluate changes in transcriptome
(2005-01-01)The serial analysis of gene expression (SAGE) method is used to study global gene expression in cells or tissues in various experimental conditions. However, its reproducibility has not yet been definitively assessed. In ... -
Virginia Bioinformatics Institute 2004 Annual Report
(Virginia Bioinformatics Institute, 2005-01-17) -
Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich
(2005-09-26)Background Eukaryotic organisms contain mitochondria, organelles capable of producing large amounts of ATP by oxidative phosphorylation. Each cell contains many mitochondria with many copies of mitochondrial DNA in each ... -
The distribution of SNPs in human gene regulatory regions
(2005-10-06)Background As a result of high-throughput genotyping methods, millions of human genetic variants have been reported in recent years. To efficiently identify those with significant biological functions, a practical strategy ... -
Virginia Bioinformatics Institute at Virginia Tech: Scientific Annual Report 2005
(Virginia Bioinformatics Institute, 2005-12-02) -
Tomato Expression Database (TED): a suite of data presentation and analysis tools
(2006-01-01)The Tomato Expression Database (TED) includes three integrated components. The Tomato Microarray Data Warehouse serves as a central repository for raw gene expression data derived from the public tomato cDNA microarray. ... -
VMD: a community annotation database for oomycetes and microbial genomes
(2006-01-01)The VBI Microbial Database (VMD) is a database system designed to host a range of microbial genome sequences. At present, the database contains genome sequence and annotation data of two plant pathogens Phytophthora sojae ... -
Innovation, Connecting to the Future: 2005 Annual Report
(Virginia Bioinformatics Institute, 2006-01-18) -
e-Connections, vol. 1, no. 1; Spring 2006
(Virginia Bioinformatics Institute, Virginia Tech, 2006-04-14) -
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
(2006-04-20)Background Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, together with a statistical significance ... -
e-Connections, vol. 1, no. 2; Summer 2006
(Virginia Bioinformatics Institute, Virginia Tech, 2006-07-06) -
Virginia Bioinformatics Institute at Virginia Tech: Scientific Annual Report 2006
(Virginia Bioinformatics Institute, 2006-08-07) -
e-Connections, vol. 1, no. 3; Fall 2006
(Virginia Bioinformatics Institute, Virginia Tech, 2006-10-03) -
GenomeBlast: a web tool for small genome comparison
(2006-12-12)Background Comparative genomics has become an essential approach for identifying homologous gene candidates and their functions, and for studying genome evolution. There are many tools available for genome comparisons. ... -
A syntactic model to design and verify synthetic genetic constructs derived from standard biological parts
(2007)Motivation: The sequence of artificial genetic constructs is composed of multiple functional fragments, or genetic parts, involved in different molecular steps of gene expression mechanisms. Biologists have deciphered ... -
GeneTrees: a phylogenomics resource for prokaryotes
(2007-01)The GeneTrees phylogenomics system pursues comparative genomic analyses from the perspective of gene phylogenies for individual genes. The GeneTrees project has the goal of providing detailed evolutionary models for all ... -
MvirDB - a microbial database of protein toxins, virulence factors and antibiotic resistance genes for bio-defence applications
(2007-01)Knowledge of toxins, virulence factors and antibiotic resistance genes is essential for bio-defense applications aimed at identifying 'functional' signatures for characterizing emerging or engineered pathogens. Whereas ...
