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Fabrication and characterization of PLGA nanoparticles encapsulating large CRISPR–Cas9 plasmid
(2020-01-20)
Background
The clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9 protein system is a revolutionary tool for gene therapy. Despite promising reports of the utility of CRISPR–Cas9 for in vivo gene ...
A Coupled OpenFOAM-WRF Study on Atmosphere-Wake-Ocean Interaction
(MDPI, 2020-12-30)
This work aims to better understand how small scale disturbances that are generated at the air-sea interface propagate into the surrounding atmosphere under realistic environmental conditions. To that end, a one-way coupled ...
Isolation of Thermally Stable Cellulose Nanocrystals from Spent Coffee Grounds via Phosphoric Acid Hydrolysis
(2020-02-01)
As the world's population exponentially grows, so does the need for the production of food, with cereal production growing annually from an estimated 1.0 billion to 2.5 billion tons within the last few decades. This rapid ...
The Impacts of the Neighborhood Built Environment on Social Capital for Middle-Aged and Elderly Koreans
(MDPI, 2021-01-14)
The purpose of this study was to investigate the relationship between the neighborhood built environment (NBE) aspects of age-friendly cities and communities (AFCCs) and social capital in the Korean context. We described ...
Homogeneous nanodiscs of native membranes formed by stilbene-maleic-acid copolymers
(2020-08-28)
Methylstilbene-alt-maleic acid copolymers spontaneously convert biological membranes into bilayer discs with similar to 20 nm diameters. This readily functionalizable class of copolymers has the compositional homogeneity, ...
Multi-Physics Modeling of Electrochemical Deposition
(MDPI, 2020-12-11)
Electrochemical deposition (ECD) is a common method used in the field of microelectronics to grow metallic coatings on an electrode. The deposition process occurs in an electrolyte bath where dissolved ions of the depositing ...
Perturbation-based balance training targeting both slip- and trip-induced falls among older adults: a randomized controlled trial
(2020-06-12)
Background
Falls are the leading cause of injuries among older adults. Perturbation-based balance training (PBT) is an innovative approach to fall prevention that aims to improve the reactive balance response following ...
Bulk and interfacial interactions between hydroxypropyl-cellulose and bile salts: Impact on the digestion of emulsified lipids
(2020-09)
Hydroxypropyl-cellulose (HPC) is a surface-active, non-digestible polysaccharide, commonly used in food emulsions as thickener and/or emulsifier. Due to these dual characteristics, HPC is a potential ingredient to modulate ...
Exceptional capacitive deionization rate and capacity by block copolymer–based porous carbon fibers
(American Association for the Advancement of Science, 2020-04-17)
Capacitive deionization (CDI) is energetically favorable for desalinating low-salinity water. The bottlenecks of current carbon-based CDI materials are their limited desalination capacities and time-consuming cycles, caused ...
Isocyanate- and solvent-free synthesis of melt processible polyurea elastomers derived from urea as a monomer
(2020-05-18)
Polyurea elastomers are utilized for a myriad of applications ranging from coatings and foams to dielectric materials for capacitors and actuators. However, current synthetic methods for polyureas rely on highly reactive ...