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Sex differences in the expression of lupus-associated miRNAs in splenocytes from lupus-prone NZB/WF1 mice
(2013-11-01)
Background
A majority of autoimmune diseases, including systemic lupus erythematosus (SLE), occur predominantly in females. Recent studies have identified specific dysregulated microRNAs (miRNAs) in both human and murine ...
Transcriptional Profiling of a Cross-Protective Salmonella enterica serovar Typhimurium UK-1 dam Mutant Identifies a Set of Genes More Transcriptionally Active Compared to Wild-Type, and Stably Transcribed across Biologically Relevant Microenvironments.
(2014)
Vaccination with Salmonella enterica serovar Typhimurium lacking DNA adenine methyltransferase confers cross-protective immunity against multiple Salmonella serotypes. The mechanistic basis is thought to be associated with ...
Spontaneous Course of Biliary Sludge Over 12 Months in Dogs with Ultrasonographically Identified Biliary Sludge
(American College of Veterinary Internal Medicine, 2016-05)
Background: Biliary sludge is associated with gallbladder (GB) dysmotility and mucus hypersecretion suggesting a link between biliary sludge, and the formation of GB mucoceles (GMT). If biliary sludge progresses to GBM, ...
Survey of Antibodies to Trypanosoma cruzi and Leishmania spp. in Gray and Red Fox Populations From North Carolina and Virginia
(American Society of Parasitology, 2010-12)
American trypanosomiasis and leishmaniasis are caused by related hemoflagellate parasites, Trypanosoma cruzi and Leishmania spp., which share several common host species. Both zoonotic protozoans are endemic in the United ...
Mutations present in a low-passage Zika virus isolate result in attenuated pathogenesis in mice
(2019-04)
Zika virus (ZIKV) infection can result in neurological disorders including Congenital Zika Syndrome in infants exposed to the virus in utero. Pregnant women can be infected by mosquito bite as well as by sexual transmission ...
Risk Factors of Porcine Cysticercosis in the Eastern Cape Province, South Africa
(PLOS, 2012-05-24)
There is a high prevalence of Taenia solium taeniosis/cysticercosis in humans and pigs in the Eastern Cape Province (ECP) of South Africa. The objective of this study was to identify risk factors of porcine cysticercosis ...
Engineering Tendon: Scaffolds, Bioreactors, and Models of Regeneration
(Hindawi, 2016)
Tendons bridge muscle and bone, translating forces to the skeleton and increasing the safety and efficiency of locomotion. When tendons fail or degenerate, there are no effective pharmacological interventions. The lack of ...
Regulation of IL-17 in autoimmune diseases by transcriptional factors and microRNAs
(Frontiers, 2015-07-14)
In recent years, IL-17A (IL-17), a pro-inflammatory cytokine, has received intense attention of researchers and clinicians alike with documented effects in inflammation and autoimmune diseases. IL-17 mobilizes, recruits ...
A Comparison of Liver Sampling Techniques in Dogs
(American College of Veterinary Internal Medicine, 2015-01)
Background: The liver sampling technique in dogs that consistently provides samples adequate for accurate histopathologic interpretation is not known. Hypothesis/ Objectives: To compare histopathologic results of liver ...
Evaluation of the Efficacy of Disinfectant Footmats for the Reduction of Bacterial Contamination on Footwear in a Large Animal Veterinary Hospital
(American College of Veterinary Internal Medicine, 2016-11)
Background: Infection control is critical to providing high-quality patient care. Many veterinary teaching hospitals (VTHs) utilize footbaths or footmats at entrances and key control points throughout the facility to ...