Now showing items 88-107 of 127

    • The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities 

      Davis, James J.; Wattam, Alice R.; Aziz, Ramy K.; Brettin, Thomas; Butler, Ralph; Butler, Rory M.; Chlenski, Philippe; Conrad, Neal; Dickerman, Allan; Dietrich, Emily M.; Gabbard, Joseph L.; Gerdes, Svetlana; Guard, Andrew; Kenyon, Ronald W.; Machi, Dustin; Mao, Chunhong; Murphy-Olson, Dan; Nguyen, Marcus; Nordberg, Eric K.; Olsen, Gary J.; Olson, Robert D.; Overbeek, Jamie C.; Overbeek, Ross; Parrello, Bruce; Pusch, Gordon D.; Shukla, Maulik; Thomas, Chris; VanOeffelen, Margo; Vonstein, Veronika; Warren, Andrew S.; Xia, Fangfang; Xie, Dawen; Yoo, Hyunseung; Stevens, Rick (2020-01-08)
      The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases (https://www.patricbrc.org). PATRIC supports ...
    • Patterns and Limitations of Urban Human Mobility Resilience under the Influence of Multiple Types of Natural Disaster 

      Wang, Qi; Taylor, John E. (Public Library of Science, 2016-01-28)
      Natural disasters pose serious threats to large urban areas, therefore understanding and predicting human movements is critical for evaluating a population’s vulnerability and resilience and developing plans for disaster ...
    • The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility 

      Zhang, Shuai; Hulver, Matthew W.; McMillan, Ryan P.; Cline, Mark A.; Gilbert, Elizabeth R. (2014-02-12)
      Metabolic flexibility is the capacity of a system to adjust fuel (primarily glucose and fatty acids) oxidation based on nutrient availability. The ability to alter substrate oxidation in response to nutritional state depends ...
    • Plant Date, Yield, and Nitrogen Management for Strawberries in the Coastal Plain of Virginia 

      Deitch, Ursula (Virginia Tech, 2016-04-25)
      Fresh market strawberry (Fragaria × ananassa) availability in mid to late -April signals the beginning of locally available fresh fruit and vegetables for the mid-Atlantic region. Of the 290 acres of fresh market strawberries ...
    • Prediabetes Phenotype Influences Improvements in Glucose Homeostasis with Resistance Training 

      Eikenberg, Joshua D.; Savla, Jyoti S.; Marinik, Elaina L.; Davy, Kevin P.; Pownall, John; Baugh, Mary E.; Flack, Kyle D.; Boshra, Soheir; Winett, Richard A.; Davy, Brenda M. (PLOS, 2016-02-03)
      Purpose To determine if prediabetes phenotype influences improvements in glucose homeostasis with resistance training (RT). Methods Older, overweight individuals with prediabetes (n = 159; aged 60±5 yrs; BMI 33±4 ...
    • Predicting Complications in Critical Care Using Heterogeneous Clinical Data 

      Huddar, Vijay; Desiraju, Bapu Koundinya; Rajan, Vaibhav; Bhattacharya, Sakyajit; Roy, Shourya; Reddy, Chandan K. (IEEE, 2016-10-19)
      Patients in hospitals, particularly in critical care, are susceptible to many complications affecting morbidity and mortality. Digitized clinical data in electronic medical records can be effectively used to develop machine ...
    • Predictors of Successful Weight Loss Maintenance: A Qualitative Comparative Analysis 

      Baugh, Mary E.; Savla, Jyoti S.; Akers, Jeremy D.; Raynor, Hollie A.; Davy, Kevin P.; Davy, Brenda M. (Scientific Research, 2014-05)
      Individuals successful at weight loss maintenance (WTLM) utilize similar behaviors but in varying amounts and combinations. Research identifying characteristics which predict WTLM success could be used to develop effective ...
    • Psychosocial constructs were not mediators of intervention effects for dietary and physical activity outcomes in a church-based lifestyle intervention: Delta Body and Soul III 

      Thomson, Jessica L.; Tussing-Humphreys, Lisa M.; Zoellner, Jamie M.; Goodman, Melissa H. (2016-08)
      Objective: Evaluating an intervention's theoretical basis can inform design modifications to produce more effective interventions. Hence the present study's purpose was to determine if effects from a multicomponent lifestyle ...
    • Quantifying Interhospital Patient Sharing as a Mechanism for Infectious Disease Spread 

      Huang, Susan S.; Avery, Takuser R.; Song, Yeohan H.; Elkins, Kristen R.; Nguyen, Christopher C.; Nutter, Sandra K.; Nafday, Alaka. A.; Condon, Curtis J.; Chang, Michael T.; Chrest, David; Boos, John; Bobashev, Georgiy; Wheaton, William; Frank, Steven A.; Platt, Richard; Lipsitch, Marc; Bush, Robin M.; Eubank, Stephen; Burke, Donald S.; Lee, Bruce Y. (University of Chicago Press, 2010-11)
      BACKGROUND. Assessments of infectious disease spread in hospitals seldom account for interfacility patient sharing. This is particularly important for pathogens with prolonged incubation periods or carrier states. METHODS. ...
    • Remodeling Lipid Metabolism and Improving Insulin Responsiveness in Human Primary Myotubes 

      Sparks, Lauren M.; Moro, Cedric; Ukropcova, Barbara; Bajpeyi, Sudip; Civitarese, Anthony E.; Hulver, Matthew W.; Thoresen, G. Hege; Rustan, Arild C.; Smith, Steven R. (PLOS, 2011-07-08)
      Objective: Disturbances in lipid metabolism are strongly associated with insulin resistance and type 2 diabetes (T2D). We hypothesized that activation of cAMP/PKA and calcium signaling pathways in cultured human myotubes ...
    • Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes 

      Davy, Brenda M.; Winett, Richard A.; Savla, Jyoti S.; Marinik, Elaina L.; Baugh, Mary Elizabeth; Flack, Kyle D.; Halliday, Tanya M.; Kelleher, Sarah A.; Winett, Sheila G.; Williams, David M.; Boshra, Soheir (PLOS, 2017-02-23)
      Objective To determine whether a social cognitive theory (SCT)-based intervention improves resistance training (RT) maintenance and strength, and reduces prediabetes prevalence. Research design and methods Sedentary, ...
    • Resistance exercise training and in vitro skeletal muscle oxidative capacity in older adults 

      Flack, Kyle D.; Davy, Brenda M.; DeBerardinis, Martin; Boutagy, Nabil E.; McMillan, Ryan P.; Hulver, Matthew W.; Frisard, Madlyn I.; Anderson, Angela S.; Savla, Jyoti S.; Davy, Kevin P. (2016-07)
      Whether resistance exercise training (RET) improves skeletal muscle substrate oxidative capacity and reduces mitochondrial production of reactive oxygen species in older adults remains unclear. To address this, 19 older ...
    • Rural physical activity interventions in the United States: a systematic review and RE-AIM evaluation 

      Bhuiyan, Nishat; Singh, Pritika; Harden, Samantha M.; Mama, Scherezade K. (2019-12-27)
      Background Previous reviews of rural physical activity interventions were focused on intervention effectiveness and had reported overall mixed findings. The purpose of this systematic review was to apply the Reach, Efficacy, ...
    • Sensitivity of Household Transmission to Household Contact Structure and Size 

      Marathe, Achla; Lewis, Bryan L.; Chen, Jiangzhuo; Eubank, Stephen (PLOS, 2011-08-01)
      Objective: Study the influence of household contact structure on the spread of an influenza-like illness. Examine whether changes to in-home care giving arrangements can significantly affect the household transmission ...
    • SIPsmartER delivered through rural, local health districts: adoption and implementation outcomes 

      Porter, Kathleen J.; Brock, Donna J.; Estabrooks, Paul A.; Perzynski, Katelynn M.; Hecht, Erin R.; Ray, Pamela; Kruzliakova, Natalie; Cantrell, Eleanor S.; Zoellner, Jamie M. (2019-09-18)
      Background SIPsmartER is a 6-month evidenced-based, multi-component behavioral intervention that targets sugar-sweetened beverages among adults. It consists of three in-person group classes, one teach-back call, and 11 ...
    • Small Molecule Kaempferol Promotes Insulin Sensitivity and Preserved Pancreatic β-Cell Mass in Middle-Aged Obese Diabetic Mice 

      Alkhalidy, Hana; Moore, William; Zhang, Yanling; McMillan, Ryan P.; Wang, Aihua; Ali, Mostafa; Suh, Kyung-Shin; Zhen, Wei; Cheng, Zhiyong; Jia, Zhenquan; Hulver, Matthew W.; Liu, Dongmin (Hindawi, 2015-05-07)
      Insulin resistance and a progressive decline in functional β-cell mass are hallmarks of developing type 2 diabetes (T2D). Thus, searching for natural, low-cost compounds to target these two defects could be a promising ...
    • Spatio-Temporal Storytelling on Twitter 

      Dos Santos Jr, Raimundo F.; Shah, Sumit; Chen, Feng; Boedihardjo, Arnold P.; Butler, Patrick; Lu, Chang-Tien; Ramakrishnan, Naren (Department of Computer Science, Virginia Polytechnic Institute & State University, 2013-12-16), TR-13-06
      Social media, e.g.,Twitter, have provided us an unprecedented opportunity to observe events un-folding in real-time. The rapid pace at which situations play out on social media necessitates new tools for capturing and ...
    • STRATEGY FOR A NATIONAL COMMUNITY LEARNING NETWORK: COMMUNITY LEARNING DATA DRIVEN DISCOVERY - Building Capacity for Evidence-Based Decision Making 

      Keller, S. A. (2016-12-19)
      The Social and Decision Analytics Laboratory (SDAL) of the Biocomplexity Institute of Virginia Tech received a planning grant from the Laura and John Arnold Foundation (LJAF) to develop a strategy for a national community ...
    • Strengthening of accountability systems to create healthy food environments and reduce global obesity 

      Swinburn, Boyd; Kraak, Vivica; Rutter, Harry; Vandevijvere, Stefanie; Lobstein, Tim; Sacks, Gary; Gomes, Fabio; Marsh, Tim; Magnusson, Roger (Elsevier, 2015)
    • Stresses and Instability in Coastal Systems: Sustaining Prosperity, Increasing Diversity and Achieving Resilience 

      Weiss, Robert; Bukvic, Anamaria; Dayer, Ashley A.; Fraser, James; Karpanty, Sarah M.; Catlin, Daniel; Juran, Luke; Wynne, Randolph H.; Gohlke, Julia; Boyle, Kevin; Irish, Jennifer L.; Leon, Roberto; Zobel, Christopher W.; Rees, Loren; Zhang, Yang; Schenk, Todd; Dixit, Priya (Virginia Tech, 2017-05-15)
      More than half of the world’s human population lives within 40 miles of the sea. Coastal cities are the backbone of global finance, trade, manufacturing, and transportation. Millions of people worldwide travel to beaches ...