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Remodeling Lipid Metabolism and Improving Insulin Responsiveness in Human Primary Myotubes

Sparks, Lauren M.; Moro, Cedric; Ukropcova, Barbara; Bajpeyi, Sudip; Civitarese, Anthony E.; Hulver, Matthew W.; Thoresen, G. Hege; Rustan, Arild C.; Smith, Steven R. (PLOS, 2011-07-08)

Objective: Disturbances in lipid metabolism are strongly associated with insulin resistance and type 2 diabetes (T2D). We hypothesized that activation of cAMP/PKA and calcium signaling pathways in cultured human myotubes ...