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Efficacy and Safety of Ephedra and Ephedrine for Weight Loss and Athletic Performance: A Meta-analysis
(AMA, 2003-03-26)
CONTEXT:
Ephedra and ephedrine sometimes are used for weight loss or enhanced athletic performance, but the efficacy and safety of these compounds are uncertain.
OBJECTIVE:
To assess the efficacy and safety of ephedra ...
Unsupervised clustering of gene expression data points at hypoxia as possible trigger for metabolic syndrome
(2006-12-19)
Background
Classification of large volumes of data produced in a microarray experiment allows for the extraction of important clues as to the nature of a disease.
Results
Using multi-dimensional unsupervised FOREL (FORmal ...
Systems Integration of Biodefense Omics Data for Analysis of Pathogen-Host Interactions and Identification of Potential Targets
(Public Library of Science, 2009-09-25)
The NIAID (National Institute for Allergy and Infectious Diseases) Biodefense Proteomics program aims to identify targets for potential vaccines, therapeutics, and diagnostics for agents of concern in bioterrorism, including ...
The molecular mechanism linking muscle fat accumulation to insulin resistance
(The Nutrition Society, 2004)
Skeletal muscle insulin resistance is a co-morbidity of obesity and a risk factor for the development of type 2 diabetes mellitus. Insulin resistance is associated with the accumulation of intramyocellular lipids. ...
A Model for a Smallpox-Vaccination Policy
(NEJM Group, 2003-01-30)
Background: The new reality of biologic terrorism and warfare has ignited a debate about whether to reintroduce smallpox vaccination.
Methods: We developed scenarios of smallpox attacks and built a stochastic model of ...
Forecasting Model for Air Taxi, Commercial Airline, and Automobile Demand in the United States
(Transportation Research Board of the National Academies, 2008)
A nationwide model predicts the annual county-to-county person roundtrips for air taxi, commercial airline, and automobile at 1-year intervals through 2030. The transportation systems analysis model (TSAM) uses the four-step ...
Effects of Omega-3 Fatty Acids on Cancer Risk
(AMA, 2006-04)
Context: Omega-3 fatty acids are purported to reduce the risk of cancer. Studies have reported mixed results.
Objective: To synthesize published and unpublished evidence to determine estimates of the effect of omega-3 ...
Interventions for the prevention of falls in older adults: systematic review and meta-analysis of randomised clinical trials
(BMJ Publishing Group Ltd, 2004-03-20)
Objective: To assess the relative effectiveness of interventions to prevent falls in older adults to either a usual care group or control group.
Design: Systematic review and meta-analyses. Data sources Medline, ...
Ephedra
(Institute of Mathematical Statistics, 2005-08)
In February 2004, the U.S. Food and Drug Administration (FDA) prohibited the sale of dietary supplements containing ephedrine alkaloids (ephedra), stating that such supplements present an unreasonable risk of illness or ...