Now showing items 21-40 of 126

    • Application of alignment-free bioinformatics methods to identify an oomycete protein with structural and functional similarity to the bacterial AvrE effector protein 

      Deb, Devdutta; Mackey, David; Opiyo, Stephen O.; McDowell, John M. (PLOS, 2018-04-11)
      Diverse plant pathogens export effector proteins to reprogram host cells. One of the most challenging goals in the molecular plant-microbe field is to functionally characterize the complex repertoires of effectors secreted ...
    • The iPlant collaborative: cyberinfrastructure for plant biology 

      Goff, Stephen A.; Vaughn, Matthew; McKay, Sheldon; Lyons, Eric; Stapleton, Ann E.; Gessler, Damian; Matasci, Naim; Wang, Liya; Hanlon, Matthew; Lenards, Andrew; Muir, Andy; Merchant, Nirav; Lowry, Sonya; Mock, Stephen; Helmke, Matthew; Kubach, Adam; Narro, Martha; Hopkins, Nicole; Micklos, David; Hilgert, Uwe; Gonzales, Michael; Jordan, Chris; Skidmore, Edwin; Dooley, Rion; Cazes, John; McLay, Robert; Lu, Zhenyuan; Pasternak, Shiran; Koesterke, Lars; Piel, William H.; Grene, Ruth; Noutsos, Christos; Gendler, Karla; Feng, Xin; Tang, Chunlao; Lent, Monica; Kim, Seung-Jin; Kvilekval, Kristian; Manjunath, B. S.; Tannen, Val; Stamatakis, Alexandros; Sanderson, Michael; Welch, Stephen M.; Cranston, Karen A.; Soltis, Pamela; Soltis, Doug; O'Meara, Brian; Ane, Cecile; Brutnell, Tom; Kleibenstein, Daniel J.; White, Jeffery W.; Leebens-Mack, James; Donoghue, Michael J.; Spalding, Edgar P.; Vision, Todd J.; Myers, Christopher R.; Lowenthal, David; Enquist, Brian J.; Boyle, Brad; Akoglu, Ali; Andrews, Greg; Ram, Sudha; Ware, Doreen; Stein, Lincoln; Stanzione, Dan (Frontiers, 2011)
      The iPlant Collaborative (iPlant) is a United States National Science Foundation (NSF) funded project that aims to create an innovative, comprehensive, and foundational cyberinfrastructure in support of plant biology ...
    • Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center 

      Wattam, Alice R.; Davis, James J.; Assaf, Rida; Boisvert, Sebastien; Brettin, Thomas; Bun, Christopher; Conrad, Neal; Dietrich, Emily M.; Disz, Terry; Gabbard, Joseph L.; Gerdes, Svetlana; Henry, Christopher S.; Kenyon, Ronald W.; Machi, Dustin; Mao, Chunhong; Nordberg, Eric K.; Olsen, Gary J.; Murphy-Olson, Daniel E.; Olson, Robert; Overbeek, Ross; Parrello, Bruce; Pusch, Gordon D.; Shukla, Maulik; Vonstein, Veronika; Warren, Andrew S.; Xia, Fangfang; Yoo, Hyunseung; Stevens, Rick L. (2017-01-04)
      The Pathosystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center (https://www.patricbrc.org). Recent changes to PATRIC include a redesign of the web interface and some new services that ...
    • Older Ghanaian adults’ perceptions of physical activity: an exploratory, mixed methods study 

      Balis, Laura E.; Sowatey, Godfred; Ansong-Gyimah, Kwame; Ofori, Eunice; Harden, Samantha M. (2019-03-15)
      Background Ghana is experiencing an epidemiological shift in public health issues toward non-communicable diseases that are underpinned by modifiable health behaviors. Physical activity rates have decreased, especially ...
    • Characterization and prediction of tropical cyclone forerunner surge 

      Liu, Yi; Irish, Jennifer L. (Elsevier, 2019)
      Forerunner surge, a water level rise ahead of tropical cyclone landfall, often strikes coastal communities unexpectedly, stranding people and increasing loss of life. Surge forecasting systems and emergency managers almost ...
    • EpiViewer: an epidemiological application for exploring time series data 

      Thorve, Swapna; Wilson, Mandy L.; Lewis, Bryan L.; Swarup, Samarth; Vullikanti, Anil Kumar S.; Marathe, Madhav V. (2018-11-22)
      Background Visualization plays an important role in epidemic time series analysis and forecasting. Viewing time series data plotted on a graph can help researchers identify anomalies and unexpected trends that could be ...
    • Connecting the Dots between PubMed Abstracts 

      Hossain, M. Shahriar; Gresock, Joseph; Edmonds, Yvette M.; Helm, Richard F.; Potts, Malcolm; Ramakrishnan, Naren (PLOS, 2012-01-03)
      Background There are now a multitude of articles published in a diversity of journals providing information about genes, proteins, pathways, and diseases. Each article investigates subsets of a biological process, but to ...
    • Mathematical Models of E-Antigen Mediated Immune Tolerance and Activation following Prenatal HBV Infection 

      Ciupe, Mihaela Stanca; Hews, Sarah (PLOS, 2012-07-02)
      We develop mathematical models for the role of hepatitis B e-antigen in creating immunological tolerance during hepatitis B virus infection and propose mechanisms for hepatitis B e-antigen clearance, subsequent emergence ...
    • Supporting maintenance of sugar-sweetened beverage reduction using automated versus live telephone support: findings from a randomized control trial 

      Zoellner, Jamie M.; You, Wen; Estabrooks, Paul A.; Chen, Yvonnes; Davy, Brenda M.; Porter, Kathleen J.; Hedrick, Valisa E.; Bailey, Angela; Kružliaková, Natalie (2018-10-04)
      Background Although reducing sugar-sweetened beverage (SSB) intake is an important behavioral strategy to improve health, no known SSB-focused behavioral trial has examined maintenance of SSB behaviors ...
    • Can a Patient's In-Hospital Length of Stay and Mortality Be Explained by Early-Risk Assessments? 

      Azadeh-Fard, Nasibeh; Ghaffarzadegan, Navid; Camelio, Jaime A. (PLOS, 2016-09-15)
      Objective To assess whether a patient’s in-hospital length of stay (LOS) and mortality can be explained by early objective and/or physicians’ subjective-risk assessments. Data Sources/Study Setting Analysis of a ...
    • Stuck in Time: Negative Income Shock Constricts the Temporal Window of Valuation Spanning the Future and the Past 

      Bickel, Warren K.; Wilson, A. George; Chen, Chen; Koffarnus, Mikhail N.; Franck, Christopher T. (PLOS, 2016-09-15)
      Insufficient resources are associated with negative consequences including decreased valuation of future reinforcers. To determine if these effects result from scarcity, we examined the consequences of acute, abrupt changes ...
    • Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis 

      Mao, Chunhong; Howard, Timothy D.; Sullivan, Dan; Fu, Zongming; Yu, Guoqiang; Parker, Sarah J.; Will, Rebecca; Vander Heide, Richard S.; Wang, Yue; Hixson, James; Van Eyk, Jennifer; Herrington, David M. (Open Access Pub, 2017-03-04)
      Factors that contribute to the onset of atherosclerosis may be elucidated by bioinformatic techniques applied to multiple sources of genomic and proteomic data. The results of genome wide association studies, such as the ...
    • Topic model-based mass spectrometric data analysis in cancer biomarker discovery studies 

      Wang, Minkun; Tsai, Tsung-Heng; Di Poto, Cristina; Ferrarini, Alessia; Yu, Guoqiang; Ressom, Habtom W. (BMC, 2016)
      Background: A fundamental challenge in quantitation of biomolecules for cancer biomarker discovery is owing to the heterogeneous nature of human biospecimens. Although this issue has been a subject of discussion in cancer ...
    • Designing for Schadenfreude (or, how to express well-being and see if youʼre boring people) 

      André, Paul; Schraefel, M.C.; Dix, Alan; White, Ryen W.; Bernstein, Michael; Luther, Kurt (ACM, 2010)
      This position paper presents two studies of content not normally expressed in status updates—well-being and status feedback—and considers how they may be processed, valued and used for potential quality-of-life benefits ...
    • CrowdLayout: Crowdsourced Design and Evaluation of Biological Network Visualizations 

      Singh, Divit P.; Lisle, Lee; Murali, T. M.; Luther, Kurt (ACM, 2018-04)
      Biologists often perform experiments whose results generate large quantities of data, such as interactions between molecules in a cell, that are best represented as networks (graphs). To visualize these networks and ...
    • Mass fatality preparedness among medical examiners/coroners in the United States: a cross-sectional study 

      Gershon, Robyn R.M.; Orr, Mark G.; Zhi, Qi; Merrill, Jacqueline A. (BMC, 2014)
      Background: In the United States (US), Medical Examiners and Coroners (ME/Cs) have the legal authority for the management of mass fatality incidents (MFI). Yet, preparedness and operational capabilities in this sector ...
    • The Theory of Reasoned Action as Parallel Constraint Satisfaction: Towards a Dynamic Computational Model of Health Behavior 

      Orr, Mark G.; Thrush, Roxanne; Plaut, David C. (PLOS, 2013-05-03)
      The reasoned action approach, although ubiquitous in health behavior theory (e.g., Theory of Reasoned Action/Planned Behavior), does not adequately address two key dynamical aspects of health behavior: learning and the ...
    • Arlington County Emergency Alerts: Enhancing Enrollment and Effectiveness 

      Grant, Milicent; Tyner, Samantha; Ziemer, Kathryn (Virginia Tech, 2017)
      Emergency alerts are an efficient tool for keeping populations well informed during high-risk situations. In collaboration with Arlington County, our laboratory conducted a pilot study to identify messaging patterns that ...
    • Predicting Complications in Critical Care Using Heterogeneous Clinical Data 

      Huddar, Vijay; Desiraju, Bapu Koundinya; Rajan, Vaibhav; Bhattacharya, Sakyajit; Roy, Shourya; Reddy, Chandan K. (IEEE, 2016-10-19)
      Patients in hospitals, particularly in critical care, are susceptible to many complications affecting morbidity and mortality. Digitized clinical data in electronic medical records can be effectively used to develop machine ...
    • Economic and Social Impact of Influenza Mitigation Strategies by Demographic Class 

      Barrett, Christopher L.; Bisset, Keith; Leidig, Jonathan; Marathe, Achla; Marathe, Madhav (Elsevier, 2011-03-01)
      Background—We aim to determine the economic and social impact of typical interventions proposed by the public health officials and preventive behavioral changes adopted by the private citizens in the event of a “flu-like” ...