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  The ‘Tommy Atkins’ mango genome reveals candidate genes for fruit quality 

  Bally, Ian S. E.; Bombarely, Aureliano; Chambers, Alan H.; Cohen, Yuval; Dillon, Natalie L.; Innes, David J.; Islas-Osuna, María A.; Kuhn, David N.; Mueller, Lukas A.; Ophir, Ron; Rambani, Aditi; Sherman, Amir; Yan, Haidong (2021-02-22)

  Background Mango, Mangifera indica L., an important tropical fruit crop, is grown for its sweet and aromatic fruits. Past improvement of this species has predominantly relied on chance seedlings derived ...
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  Validated Analytical Modeling of Diesel Engines Intake Manifold with a Flexible Crankshaft 

  Elmoselhy, Salah A.M.; Faris, Waleed F.; Rakha, Hesham A. (MDPI, 2021-02-26)

  The flexibility of a crankshaft exhibits significant nonlinearities in the analysis of diesel engines performance, particularly at rotational speeds of around 2000 rpm. Given the explainable mathematical trends of the ...
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  Investigating the Impact of Brief Outings on the Welfare of Dogs Living in US Shelters 

  Gunter, Lisa M.; Gilchrist, Rachel J.; Blade, Emily M.; Barber, Rebecca T.; Feuerbacher, Erica N.; Platzer, JoAnna M.; Wynne, Clive D. L. (MDPI, 2021-02-19)

  Social isolation likely contributes to reduced welfare for shelter-living dogs. Several studies have established that time out of the kennel with a person can improve dogs’ behavior and reduce physiological measures of ...
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  An Engineered Reporter Phage for the Fluorometric Detection of Escherichia coli in Ground Beef 

  Chen, Anqi; Wang, Danhui; Nugen, Sam R.; Chen, Juhong (MDPI, 2021-02-19)

  Despite enhanced sanitation implementations, foodborne bacterial pathogens still remain a major threat to public health and generate high costs for the food industry. Reporter bacteriophage (phage) systems have been regarded ...
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  Lifelong Ulk1-Mediated Autophagy Deficiency in Muscle Induces Mitochondrial Dysfunction and Contractile Weakness 

  Nichenko, Anna S.; Sorensen, Jacob R.; Southern, W. Michael; Qualls, Anita E.; Schifino, Albino G.; McFaline-Figueroa, Jennifer; Blum, Jamie E.; Tehrani, Kayvan F.; Yin, Hang; Mortensen, Luke J.; Thalacker-Mercer, Anna E.; Greising, Sarah M.; Call, Jarrod A. (MDPI, 2021-02-16)

  The accumulation of damaged mitochondria due to insufficient autophagy has been implicated in the pathophysiology of skeletal muscle aging. Ulk1 is an autophagy-related kinase that initiates autophagosome assembly and may ...
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  Physical Mapping of the Anopheles (Nyssorhynchus) darlingi Genomic Scaffolds 

  Rafael, Míriam Silva; Bridi, Leticia Cegatti; Sharakhov, Igor V.; Marinotti, Osvaldo; Sharakhova, Maria V.; Timoshevskiy, Vladimir; Guimarães-Marques, Giselle Moura; Santos, Valéria Silva; da Silva, Carlos Gustavo Nunes; Astolfi-Filho, Spartaco; Tadei, Wanderli Pedro (MDPI, 2021-02-15)

  The genome assembly of Anopheles darlingi consists of 2221 scaffolds (N50 = 115,072 bp) and has a size spanning 136.94 Mbp. This assembly represents one of the smallest genomes among Anopheles species. ...
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  Dietary Anti-Aging Polyphenols and Potential Mechanisms 

  Luo, Jing; Si, Hongwei; Jia, Zhenquan; Liu, Dongmin (MDPI, 2021-02-13)

  For years, the consumption of a diet rich in fruits and vegetables has been considered healthy, increasing longevity, and decreasing morbidities. With the assistance of basic research investigating the potential mechanisms, ...
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  Resveratrol Inhibits Venezuelan Equine Encephalitis Virus Infection by Interfering with the AKT/GSK Pathway 

  Lehman, Caitlin W.; Kehn-Hall, Kylene; Aggarwal, Megha; Bracci, Nicole R.; Pan, Han-Chi; Panny, Lauren; Lamb, Robert A.; Lin, Shih-Chao (MDPI, 2021-02-12)

  The host proteins Protein Kinase B (AKT) and glycogen synthase kinase-3 (GSK-3) are associated with multiple neurodegenerative disorders. They are also important for the replication of Venezuelan equine encephalitis virus ...
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  Transcriptome Response of Liver and Muscle in Heat-Stressed Laying Hens 

  Wang, Yan; Jia, Xinzheng; Hsieh, John C. F.; Monson, Melissa S.; Zhang, Jibin; Shu, Dingming; Nie, Qinghua; Persia, Michael E.; Rothschild, Max F.; Lamont, Susan J. (MDPI, 2021-02-10)

  Exposure to high ambient temperature has detrimental effects on poultry welfare and production. Although changes in gene expression due to heat exposure have been well described for broiler chickens, knowledge of the effects ...
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  A Gene-Based Method for Cytogenetic Mapping of Repeat-Rich Mosquito Genomes 

  Masri, Reem A.; Karagodin, Dmitriy A.; Sharma, Atashi; Sharakhova, Maria V. (MDPI, 2021-02-06)

  Long-read sequencing technologies have opened up new avenues of research on the mosquito genome biology, enabling scientists to better understand the remarkable abilities of vectors for transmitting pathogens. Although new ...
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  Evaluation of Seismic Vulnerability of Hospitals in the Tehran Metropolitan Area 

  Ghaychi Afrouz, Setareh; Farzampour, Alireza; Hejazi, Zahra; Mojarab, Masoud (MDPI, 2021-02-05)

  The Tehran metropolitan area is extremely vulnerable to earthquakes due to the location of its active faults and its dense population. Assessing the probable damage of a high magnitude earthquake on buildings and facilities ...
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  GCA: an R package for genetic connectedness analysis using pedigree and genomic data 

  Yu, Haipeng; Morota, Gota (2021-02-15)

  Background Genetic connectedness is a critical component of genetic evaluation as it assesses the comparability of predicted genetic values across units. Genetic connectedness also plays an essential role ...
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  Standard Propagation Channel Models for MIMO Communication Systems 

  Imoize, Agbotiname Lucky; Ibhaze, Augustus Ehiremen; Atayero, Aderemi A.; Kavitha, K. V. N. (Hindawi, 2021-02-16)

  The field of wireless communication networks has witnessed a dramatic change over the last decade due to sophisticated technologies deployed to satisfy various demands peculiar to different data-intensive wireless applications. ...
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  A case of congenital ureteral atresia causing rare upper and lower urinary tract manifestations in a puppy: a case report 

  Zalek, Megan; Shah, Rohan; Bolton, Timothy (2021-02-09)

  Background Ureteral atresia is the congenital absence of a ureteral opening, resulting in a blind-ended ureter that fails to terminate at the urinary bladder. Consequently, severe hydroureter and hydronephrosis ...
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  Utilizing Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Analyze Interstitial Fluid Flow and Transport in Glioblastoma and the Surrounding Parenchyma in Human Patients 

  Chatterjee, Krishnashis; Atay, Naciye; Abler, Daniel; Bhargava, Saloni; Sahoo, Prativa; Rockne, Russell C.; Munson, Jennifer M. (MDPI, 2021-02-04)

  Background: Glioblastoma (GBM) is the deadliest and most common brain tumor in adults, with poor survival and response to aggressive therapy. Limited access of drugs to tumor cells is one reason for such grim clinical ...
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  Association of RERG Expression with Female Survival Advantage in Malignant Pleural Mesothelioma 

  De Rienzo, Assunta; Coleman, Melissa H.; Yeap, Beow Y.; Severson, David T.; Wadowski, Benjamin; Gustafson, Corinne E.; Jensen, Roderick V.; Chirieac, Lucian R.; Richards, William G.; Bueno, Raphael (MDPI, 2021-02-02)

  Sex differences in incidence, prognosis, and treatment response have been described for many cancers. In malignant pleural mesothelioma (MPM), a lethal disease associated with asbestos exposure, men outnumber women 4 to ...
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  Habitat Suitability and Establishment Limitations of a Problematic Liana 

  Dickinson, Christopher C.; Jelesko, John G.; Barney, Jacob N. (MDPI, 2021-01-29)

  The US native liana, poison ivy (Toxicodendron radicans), responsible for contact dermatitis in humans, is a competitive weed with great potential for expansion in disturbed habitats. To facilitate a better understanding ...
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  The Emerging Role of Polyphenols in the Management of Type 2 Diabetes 

  Wang, Yao; Alkhalidy, Hana; Liu, Dongmin (MDPI, 2021-01-29)

  Type 2 diabetes (T2D) is a fast-increasing health problem globally, and it results from insulin resistance and pancreatic β-cell dysfunction. The gastrointestinal (GI) tract is recognized as one of the major regulatory ...
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  Seasonal Captures of Trissolcus japonicus (Ashmead) (Hymenoptera: Scelionidae) and the Effects of Habitat Type and Tree Species on Detection Frequency 

  Quinn, Nicole F.; Talamas, Elijah J.; Leskey, Tracy C.; Bergh, J. Christopher (MDPI, 2021-01-29)

  Trissolcus japonicus, an important egg parasitoid of Halyomorpha halys in Asia, was first detected in the USA in 2014. To evaluate the effect of habitat and the seasonality of T. japonicus detections ...
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  Label-Free Quantitative Proteomics Analysis in Susceptible and Resistant Brassica napus Cultivars Infected with Xanthomonas campestris pv. campestris 

  Islam, Md Tabibul; Lee, Bok-Rye; La, Van Hien; Bae, Dong-Won; Jung, Woo-Jin; Kim, Tae-Hwan (MDPI, 2021-01-27)

  Black rot, caused by Xanthomonas campestris pv. campestris (Xcc), is the main disease of cruciferous vegetables. To characterize the resistance mechanism in the Brassica napus–Xcc ...

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