Now showing items 288-304 of 304

    • Underlying Principles of a Covid-19 Behavioral Vaccine for a Sustainable Cultural Change 

      Couto, Kalliu Carvalho; Moura Lorenzo, Flora; Tagliabue, Marco; Henriques, Marcelo Borges; Freitas Lemos, Roberta (MDPI, 2020-12-04)
      Until pharmacological measures are effective at containing the COVID-19 outbreak, adopting protective behaviors is paramount. In this work, we aim at informing interventions to limit the spread of the contagion and prepare ...
    • Using fMRI to Study Valuation and Choice 

      Montague, P. Read; Harvey, Ann H.; Kirk, Ulrich (InTech Open, 2014-05-31)
      The ability to make decisions relies on brain mechanisms designed to value our environment and elicit appropriate actions based on those values. These mechanisms allow an agent to predict the value of a potential action ...
    • Using the RE-AIM framework to evaluate physical activity public health programs in México 

      Jauregui, Edtna; Pacheco, Ann M.; Soltero, Erica G.; O’Connor, Teresia M.; Castro, Cynthia M.; Estabrooks, Paul A.; McNeill, Lorna H.; Lee, Rebecca E. (2015-02-19)
      Background Physical activity (PA) public health programming has been widely used in Mexico; however, few studies have documented individual and organizational factors that might be used to evaluate their public health ...
    • Utility of Real-Time PCR for Detection of Exserohilum rostratum in Body and Tissue Fluids during the Multistate Outbreak of Fungal Meningitis and Other Infections 

      Gade, Lalitha; Grgurich, Dale E.; Kerkering, Thomas M.; Brandt, Mary E.; Litvintseva, Anastasia P. (American Society for Microbiology, 2015)
      Exserohilum rostratum was the major cause of the multistate outbreak of fungal meningitis linked to contaminated injections of methylprednisolone acetate produced by the New England Compounding Center. Previously, we ...
    • Utilizing Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Analyze Interstitial Fluid Flow and Transport in Glioblastoma and the Surrounding Parenchyma in Human Patients 

      Chatterjee, Krishnashis; Atay, Naciye; Abler, Daniel; Bhargava, Saloni; Sahoo, Prativa; Rockne, Russell C.; Munson, Jennifer M. (MDPI, 2021-02-04)
      Background: Glioblastoma (GBM) is the deadliest and most common brain tumor in adults, with poor survival and response to aggressive therapy. Limited access of drugs to tumor cells is one reason for such grim clinical ...
    • Validity and Repeatability of Single-Sensor Loadsol Insoles during Landing 

      Peebles, Alexander T.; Maguire, Lindsay A.; Renner, Kristen E.; Queen, Robin M. (MDPI, 2018-11-22)
      Clinically feasible methods for quantifying landing kinetics could help identify patients at risk for secondary anterior cruciate ligament injuries. The purpose of this study was to evaluate the validity and between-day ...
    • Valuation in major depression is intact and stable in a non-learning environment 

      Chung, Dongil; Kadlec, Kelly; Aimone, Jason A.; McCurry, Katherine; King-Casas, Brooks; Chiu, Pearl H. (Nature, 2017-03-10)
      The clinical diagnosis and symptoms of major depressive disorder (MDD) have been closely associated with impairments in reward processing. In particular, various studies have shown blunted neural and behavioral responses ...
    • Valuation of peers’ safe choices is associated with substance-naïveté in adolescents 

      Chung, Dongil; Orloff, Mark A.; Lauharatanahirun, Nina; Chiu, Pearl H.; King-Casas, Brooks (National Academy of Sciences, 2020-11-30)
      Social influences on decision-making are particularly pronounced during adolescence and have both protective and detrimental effects. To evaluate how responsiveness to social signals may be linked to substance use in ...
    • Variations in maternal vitamin A intake modifies phenotypes in a mouse model of 22q11.2 deletion syndrome 

      Yitsege, Gelila; Stokes, Bethany A.; Sabatino, Julia A.; Sugrue, Kelsey F.; Banyai, Gabor; Paronett, Elizabeth M.; Karpinski, Beverly A.; Maynard, Thomas M.; LaMantia, Anthony-Samuel; Zohn, Irene E. (2020-10)
      Background Vitamin A regulates patterning of the pharyngeal arches, cranial nerves, and hindbrain that are essential for feeding and swallowing. In the LgDel mouse model of 22q11.2 deletion syndrome (22q11DS), morphogenesis ...
    • Visualizing Nanoparticle Mobility in Liquid at Atomic Resolution 

      Dukes, Madeline J.; Jacobs, Benjamin W.; Morgan, David G.; Hegde, Harshad; Kelly, Deborah F. (The Royal Society of Chemistry, 2013-02-28)
      Gold nanorods are widely known for their photothermal properties to treat solid tumors. Our work demonstrates the unrealized capacity to image these reagents in liquid at high resolution using Transmission Electron Microscopy ...
    • Visualizing virus particle mobility in liquid at the nanoscale 

      Varano, A. Cameron; Rahimi, Amina; Dukes, Madeline J.; Poelzing, Steven; McDonald, Sarah M.; Kelly, Deborah F. (The Royal Society of Chemistry, 2015-09-04)
      Currently, there remains a critical need to develop real-time imaging resources for life sciences. Here, we demonstrate the use of high resolution in situ imaging to observe biological complexes in liquid at the nanoscale. ...
    • Weekly Doxorubicin Increases Coronary Arteriolar Wall and Adventitial Thickness 

      Eckman, Delrae M.; Stacey, R. Brandon; Rowe, Robert; D'Agostino, Ralph, Jr.; Kock, Nancy D.; Sane, David C.; Torti, Frank M.; Yeboah, Joseph; Workman, Susan; Lane, Kimberly S.; Hundley, W. Gregory (PLOS, 2013-02-21)
      Background Doxorubicin (DOX) is associated with premature cardiovascular events including myocardial infarction. This study was performed to determine if the weekly administration of DOX influenced coronary arteriolar ...
    • What is value—accumulated reward or evidence? 

      Friston, Karl; Adams, Rick; Montague, P. Read (Frontiers, 2012-11-02)
      Why are you reading this abstract? In some sense, your answer will cast the exercise as valuable-but what is value? In what follows, we suggest that value is evidence or, more exactly, log Bayesian evidence. This implies ...
    • When Things Are Better or Worse than Expected: The Medial Frontal Cortex and the Allocation of Processing Resources 

      Potts, Geoffrey F.; Martin, Laura E.; Burton, Philip; Montague, P. Read (MIT, 2006)
      Access to limited-capacity neural systems of cognitive control must be restricted to the most relevant information. How the brain identifies and selects items for preferential processing is not fully understood. Anatomical ...
    • Women Physicians: Gender and the Medical Workplace 

      Rouse, Linda P.; Nagy-Agren, Stephanie E.; Gebhard, Roberta E.; Bernstein, Wendy K. (Mary Ann Liebert, 2020-01-20)
      Understanding the work habits, attitudes, and experiences of women physicians is critical for optimal patient care. An analysis of the medical literature (1990–2017) was undertaken to answer the following question: how are ...
    • X-linked intellectual disability gene CASK regulates postnatal brain growth in a non-cell autonomous manner 

      Srivastava, Sarika; McMillan, Ryan P.; Willis, Jeffery; Clark, Helen R.; Chavan, Vrushali; Liang, Chen; Zhang, Haiyan; Hulver, Matthew W.; Mukherjee, Konark (BMC, 2016-03-31)
      The phenotypic spectrum among girls with heterozygous mutations in the X-linked intellectual disability (XLID) gene CASK (calcium/calmodulin-dependent serine protein kinase) includes postnatal microcephaly, ponto-cerebellar ...
    • Zika Virus Persistently and Productively Infects Primary Adult Sensory Neurons In Vitro 

      Swartwout, Brianna K.; Zlotnick, Marta G.; Saver, Ashley E.; McKenna, Caroline M.; Bertke, Andrea S. (MDPI, 2017-10-13)
      Zika virus (ZIKV) has recently surged in human populations, causing an increase in congenital and Guillain-Barré syndromes. While sexual transmission and presence of ZIKV in urine, semen, vaginal secretions, and saliva ...