From 2001–2018, a series of fuel reduction and ecosystem restoration treatments were implemented in the southern Appalachian Mountains near Asheville, North Carolina, USA. Treatments consisted of prescribed fire (four burns), mechanical cutting of understory shrubs and mid-story trees (two cuttings), and a combination of both cutting and prescribed fire (two cuts + four burns). Soils were sampled in 2018 to determine potential treatment impacts for O horizon and mineral soil (0–10 cm depth) carbon (C) and nitrogen (N) and mineral soil calcium (Ca), magnesium (Mg), phosphorus (P), potassium (K), and pH. Results suggested that mean changes in O horizon C and N and mineral soil C, N, C:N, Ca, and P from 2001–2018 differed between the treatments, but only mineral soil C, N, C:N, and Ca displayed differences between at least one fuel reduction treatment and the untreated control. One soils-related restoration objective was mineral soil N reduction and the cut + burn treatment best achieved this result. Increased organic matter recalcitrance was another priority, but this was not obtained with any treatment. When paired with previously reported fuels and vegetation results from this site, it appeared that continued use of the cut + burn treatment may best achieve long-term management objectives for this site and other locations being managed for similar long-term restoration and fuels management objectives.