Browsing by Author "Wang, Z. A."

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    Label-free DNA sequence detection using oligonucleotide functionalized optical fiber
    Wang, X. W.; Cooper, K. L.; Wang, Anbo; Xu, J. C.; Wang, Z. A.; Zhang, Y.; Tu, Zhijian Jake (AIP Publishing, 2006-10-01)
    The authors present a label-free method for direct detection of deoxyribonucleic acid (DNA) sequences. The capture DNA is immobilized onto the surface of a silica optical fiber tip by means of the layer-by-layer electrostatic self-assembly technique. Hybridization of target DNA with complementary capture DNA increases the optical thickness of the fiber tip. This phenomenon can be detected by demodulation of the spectrum of a Fabry-Perot cavity fabricated in the optical fiber. Experimental results demonstrate sequence specificity and sensitivity to nanogram quantities of target DNA sequences with short (similar to 5 min) hybridization time. (c) 2006 American Institute of Physics.
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    Micro-Air-Gap Based Intrinsic Fabry-Perot Interferometric Fiber-Optic Sensor
    Chen, X. P.; Shen, F. B.; Wang, Z. A.; Huang, Z. Y.; Wang, Anbo (Optical Society of America, 2006-05-01)
    A simple intrinsic Fabry-Perot interferometric (IFPI) sensor is developed. The sensor is fabricated by two micro air gaps as reflective mirrors in a fiber to form a Fabry-Perot cavity. Theoretical and experimental studies of the sensor are described. Experimental results show that high resolution and high sensitivity can be achieved. Two structures of micro-air-gap-based IFPI sensors offer more applications than other IFPI sensors. (c) 2006 Optical Society of America.