Browsing Journal Articles, BioMed Central and SpringerOpen by Title
Now showing items 268-287 of 501
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A major genetic locus controlling natural Plasmodium falciparum infection is shared by East and West African Anopheles gambiae
(2007-07-06)Background Genetic linkage mapping identified a region of chromosome 2L in the Anopheles gambiae genome that exerts major control over natural infection by Plasmodium falciparum. This 2L Plasmodium-resistance interval was ... -
Many-to-many space-time network coding for amplify-and-forward cooperative networks: node selection and performance analysis
(2014-03-26)In this paper, the multinode amplify-and-forward cooperative communications for a network of N nodes is studied via the novel concept of many-to-many space-time network coding (M2M-STNC). Communication under the M2M-STNC ... -
mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks
(2013-12-09)Background Identification of cooperative gene regulatory network is an important topic for biological study especially in cancer research. Traditional approaches suffer from large noise in gene expression data and false ... -
Mass fatality preparedness among medical examiners/coroners in the United States: a cross-sectional study
(BMC, 2014)Background: In the United States (US), Medical Examiners and Coroners (ME/Cs) have the legal authority for the management of mass fatality incidents (MFI). Yet, preparedness and operational capabilities in this sector ... -
Measuring the activity of BioBrick promoters using an in vivo reference standard
(2009-03-20)Background The engineering of many-component, synthetic biological systems is being made easier by the development of collections of reusable, standard biological parts. However, the complexity of biology makes it difficult ... -
Meiotic crossovers are associated with open chromatin and enriched with Stowaway transposons in potato
(Biomed Central Ltd, 2017-10-30)Background: Meiotic recombination is the foundation for genetic variation in natural and artificial populations of eukaryotes. Although genetic maps have been developed for numerous plant species since the late 1980s, few ... -
Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines
(2014-05-03)Background Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when administered ... -
Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects
(2016-11-22)Abstract Background Environmentally influenced phenotypes, such as obesity and insulin resistance, can be transmitted over multiple generations. Epigenetic modifications, such ... -
Mercury concentrations in blood and feathers of nestling Bald Eagles in coastal and inland Virginia
(2019-01-19)Abstract Background Mercury (Hg) and methylmercury are widely considered significant issues for wildlife, and in particular, piscivorous birds due to their widespread availability ... -
Metabolic engineering of Saccharomyces cerevisiae to produce 1-hexadecanol from xylose
(2016-02-01)Background An advantageous but challenging approach to overcome the limited supply of petroleum and relieve the greenhouse effect is to produce bulk chemicals from renewable materials. Fatty alcohols, with a billion-dollar ... -
Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052
(2011-08-16)Background Solventogenic clostridia offer a sustainable alternative to petroleum-based production of butanol--an important chemical feedstock and potential fuel additive or replacement. C. beijerinckii is an attractive ... -
Metapopulation viability of an endangered shorebird depends on dispersal and human-created habitats: piping plovers (Charadrius melodus) and prairie rivers
(2016-03-15)Background Many species are distributed as metapopulations in dynamic landscapes, where habitats change through space and time. Individuals locate habitat through dispersal, and the relationship between a species and ... -
A methodology for deriving the sensitivity of pooled testing, based on viral load progression and pooling dilution
(2019-08-06)Abstract Background Pooled testing, in which biological specimens from multiple subjects are combined into a testing pool and tested via a single test, is a common testing ... -
Microvascular bioengineering: a focus on pericytes
(2019-03-29)Capillaries within the microcirculation are essential for oxygen delivery and nutrient/waste exchange, among other critical functions. Microvascular bioengineering approaches have sought to recapitulate many key features ... -
Missing genes in the annotation of prokaryotic genomes
(2010-03-15)Background Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports that prokaryotic gene finder programs have ... -
Mitigation of impedance changes due to electroporation therapy using bursts of high-frequency bipolar pulses
(2015-08-27)Background For electroporation-based therapies, accurate modeling of the electric field distribution within the target tissue is important for predicting the treatment volume. In response to conventional, unipolar pulses, ... -
Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich
(2005-09-26)Background Eukaryotic organisms contain mitochondria, organelles capable of producing large amounts of ATP by oxidative phosphorylation. Each cell contains many mitochondria with many copies of mitochondrial DNA in each ... -
Mixed methods evaluation of implementation and outcomes in a community-based cancer prevention intervention
(2019-08-05)Abstract Background Community-based educational programs can complement clinical strategies to increase cancer screenings and encourage healthier lifestyles to reduce cancer ... -
Model-Driven Validation of SystemC Designs
(2008-04-21)Functional test generation for dynamic validation of current system level designs is a challenging task. Manual test writing or automated random test generation techniques are often used for such validation practices. ... -
Modeling allele-specific expression at the gene and SNP levels simultaneously by a Bayesian logistic mixed regression model
(2019-10-28)Background High-throughput sequencing experiments, which can determine allele origins, have been used to assess genome-wide allele-specific expression. Despite the amount of data generated from high-throughput ...
