Search
Now showing items 1-2 of 2
A Model of Yeast Cell-Cycle Regulation Based on a Standard Component Modeling Strategy for Protein Regulatory Networks
(PLOS, 2016-05-17)
To understand the molecular mechanisms that regulate cell cycle progression in eukaryotes, a variety of mathematical modeling approaches have been employed, ranging from Boolean networks and differential equations to ...
Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model
(Biomed Central Ltd, 2013-06-28)
Background 'Parameter estimation from experimental data is critical for mathematical modeling of protein regulatory networks. For realistic networks with dozens of species and reactions, parameter estimation is an especially ...