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dc.contributor.authorDeshommes, Eliseen_US
dc.contributor.authorTardif, Roberten_US
dc.contributor.authorEdwards, Marc A.en_US
dc.contributor.authorSauvé, Sébastienen_US
dc.contributor.authorPrévost, Michèleen_US
dc.date.accessioned2013-01-17T16:04:58Z
dc.date.available2013-01-17T16:04:58Z
dc.date.issued2012-11-22
dc.identifier.citationChemistry Central Journal. 2012 Nov 22;6(1):138en_US
dc.identifier.urihttp://hdl.handle.net/10919/19162
dc.description.abstractIn vivo estimations of Pb particle bioavailability are costly and variable, because of the nature of animal assays. The most feasible alternative for increasing the number of investigations carried out on Pb particle bioavailability is in vitro testing. This testing method requires calibration using in vivo data on an adapted animal model, so that the results will be valid for childhood exposure assessment. Also, the test results must be reproducible within and between laboratories. The Relative Bioaccessibility Leaching Procedure, which is calibrated with in vivo data on soils, presents the highest degree of validation and simplicity. This method could be applied to Pb particles, including those in paint and dust, and those in drinking water systems, which although relevant, have been poorly investigated up to now for childhood exposure assessment.en_US
dc.format.mimetypeapplication/pdf
dc.language.isoen_US
dc.rightsCreative Commons Attribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleExperimental determination of the oral bioavailability and bioaccessibility of lead particlesen_US
dc.typeArticle - Refereed
dc.date.updated2013-01-17T16:04:59Z
dc.description.versionPeer Reviewed
dc.rights.holderElise Deshommes et al.; licensee BioMed Central Ltd.en_US
dc.contributor.departmentCivil and Environmental Engineeringen_US
dc.title.serialChemistry Central Journal
dc.identifier.doihttps://doi.org/10.1186/1752-153X-6-138
dc.type.dcmitypeText


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Creative Commons Attribution 4.0 International
License: Creative Commons Attribution 4.0 International