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dc.contributor.authorDeshommes, Eliseen_US
dc.contributor.authorTardif, Roberten_US
dc.contributor.authorEdwards, Marcen_US
dc.contributor.authorSauvé, Sébastienen_US
dc.contributor.authorPrévost, Michèleen_US
dc.identifier.citationChemistry Central Journal. 2012 Nov 22;6(1):138en_US
dc.description.abstractAbstract In vivo estimations of Pb particle bioavailability are costly and variable, because of the nature of animal assays. The most feasible alternative for increasing the number of investigations carried out on Pb particle bioavailability is in vitro testing. This testing method requires calibration using in vivo data on an adapted animal model, so that the results will be valid for childhood exposure assessment. Also, the test results must be reproducible within and between laboratories. The Relative Bioaccessibility Leaching Procedure, which is calibrated with in vivo data on soils, presents the highest degree of validation and simplicity. This method could be applied to Pb particles, including those in paint and dust, and those in drinking water systems, which although relevant, have been poorly investigated up to now for childhood exposure assessment.en_US
dc.rightsAttribution 4.0 United States*
dc.titleExperimental determination of the oral bioavailability and bioaccessibility of lead particlesen_US
dc.typeJournal articleen_US
dc.description.versionPeer Revieweden_US
dc.rights.holderElise Deshommes et al.; licensee BioMed Central Ltd.en_US

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