Now showing items 1-2 of 2

    • ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic model of ChIP-seq profiles 

      Chen, Xi; Jung, Jin-Gyoung; Shajahan-Hag, Ayesha N.; Clarke, Robert; Shih, Ie-Ming; Wang, Yue; Magnani, Luca; Wang, Tian-Li; Xuan, Jianhua (Oxford, 2015-12-23)
      Chromatin immunoprecipitation with massively parallel DNA sequencing (ChIP-seq) has greatly improved the reliability with which transcription factor binding sites (TFBSs) can be identified from genome-wide profiling studies. ...
    • Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites 

      Thiaville, Michelle M.; Stoeck, Alexander; Chen, Li; Wu, Ren-Chin; Magnani, Luca; Oidtman, Jessica; Shih, Ie-Ming; Lupien, Mathieu; Wang, Tian-Li (PLOS, 2012-05-02)
      PBX1 is a TALE homeodomain transcription factor involved in organogenesis and tumorigenesis. Although it has been shown that ovarian, breast, and melanoma cancer cells depend on PBX1 for cell growth and survival, the ...