Now showing items 277-296 of 503

    • Necessary, Yet Dissociable Contributions of the Insular and Ventromedial Prefrontal Cortices to Norm Adaptation: Computational and Lesion Evidence in Humans 

      Gu, Xiaosi; Wang, Xingchao; Hula, Andreas; Wang, Shiwei; Xu, Shuai; Lohrenz, Terry M.; Knight, Robert T.; Gao, Zhixian; Dayan, Peter; Montague, P. Read (Society for Neuroscience, 2015-01-14)
      Social norms and their enforcement are fundamental to human societies. The ability to detect deviations from norms and to adapt to norms in a changing environment is therefore important to individuals’ normal social ...
    • Neonatal maternal separation stress elicits lasting DNA methylation changes in the hippocampus of stress-reactive Wistar Kyoto rats 

      McCoy, Chelsea R.; Rana, Samir; Stringfellow, Sara anne; Day, Jeremy; Wyss, J. Michael; Clinton, Sarah M.; Kerman, Ilan A. (Wiley-Blackwell, 2016-11-01)
      Early-life stress (ELS) can alter neurodevelopment in variable ways, ranging from producing deleterious outcomes to stress resilience. While most ELS studies focus on its harmful effects, recent work by our lab and others ...
    • Neural computations underlying social risk sensitivity 

      Lauharatanahirun, Nina; Christopoulos, George I.; King-Casas, Brooks (Frontiers, 2012-08-02)
      Under standard models of expected utility, preferences over stochastic events are assumed to be independent of the source of uncertainty. Thus, in decision-making, an agent should exhibit consistent preferences, regardless ...
    • Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa 

      McAdams, Carrie J.; Jeon-Slaughter, Haekyung; Evans, Siobahn; Lohrenz, Terry; Montague, P. Read; Krawczyk, Daniel C. (Oxford, 2016-06-27)
      Anorexia nervosa (AN) is a severe mental illness characterized by problems with self-perception. Whole-brain neural activations in healthy women, women with AN and women in long-term weight recovery following AN were ...
    • Neural masses and fields in dynamic causal modeling 

      Moran, Rosalyn; Pinotsis, Dimitris A.; Friston Karl (Frontiers, 2013-05-28)
      Dynamic causal modeling (DCM) provides a framework for the analysis of effective connectivity among neuronal subpopulations that subtend invasive (electrocorticograms and local field potentials) and non-invasive ...
    • Neural mechanisms of negative reinforcement in children and adolescents with autism spectrum disorders 

      Cara R. Damiano; Dillon C Cockrell; Kaitlyn Dunlap; Eleanor K. Hanna; Stephanie Miller; Joshua Bizzell; Megan Kovac; Lauren Turner-Brown; John Sideris; Jessica L. Kinard; Gabriel S. Dichter (Springer New York, 2015-03-25)
      Background; Previous research has found accumulating evidence for atypical reward processing in autism spectrum disorders (ASD), particularly in the context of social rewards. Yet, this line of research has focused largely ...
    • Neural responses to sanction threats in two-party economic exchange 

      Li, Jian; Xiao, Erte; Houser, Daniel; Montague, P. Read (NAS, 2009-08-11)
      Sanctions are used ubiquitously to enforce obedience to social norms. However, recent field studies and laboratory experiments have demonstrated that cooperation is sometimes reduced when incentives meant to promote prosocial ...
    • Neural signature of fictive learning signals in a sequential investment task 

      Lohrenz, Terry; McCabe, Kevin; Camerer, Colin F.; Montague, P. Read (NAS, 2007-04-13)
      Reinforcement learning models now provide principled guides for a wide range of reward learning experiments in animals and humans. One key learning (error) signal in these models is experiential and reports ongoing temporal ...
    • Neural signatures of strategic types in a two-person bargaining game 

      Bhatt, Meghana A.; Lohrenz, Terry; Camerer, Colin F.; Montague, P. Read (NAS, 2010-09-28)
      The management and manipulation of our own social image in the minds of others requires difficult and poorly understood computations. One computation useful in social image management is strategic deception: our ability ...
    • Neuroeconomic measures of social decision-making across the lifespan 

      Zhu, Lusha; Walsh, Daniel; Hsu, Ming (Frontiers, 2012-09-21)
      Social and decision-making deficits are often the first symptoms of a striking number of neurodegenerative disorders associated with aging.These includes not only disorders that directly impact dopamine and basal ganglia, ...
    • Neuroimaging after mild traumatic brain injury: Review and meta-analysis 

      Eierud, Cyrus; Craddock, R. Cameron; Fletcher, Sean; Aulakh, Manek; King-Casas, Brooks; Kuehl, Damon; LaConte, Stephen M. (Elsevier, 2014-01-04)
      This paper broadly reviews the study of mild traumatic brain injury (mTBI), across the spectrum of neuroimaging modalities. Among the range of imaging methods, however, magnetic resonance imaging (MRI) is unique in its ...
    • Neuroimaging Strategies Addressing Challenges in Using fMRI for the Children with Cerebral Palsy 

      Lee-Park, Juniper J.; Deshpande, Harshawardhan; Lisinski, Jonathan; LaConte, Stephen M.; Ramey, Sharon Landesman; DeLuca, Stephanie C. (Scientific Research Publishing Inc., 2018-05-17)
      Aim: This study sought to develop a process and methodology that could be a useful clinical and research tool for successfully completing functional magnetic resonance imaging (fMRI) scanning in children with Cerebral ...
    • Neuroimaging, neuromodulation, and population health: the neuroscience of chronic disease prevention 

      Hall, Peter A.; Bickel, Warren K.; Erickson, Kirk I.; Wagner, Dylan D. (2018-09)
      Preventable chronic diseases are the leading cause of death in the majority of countries throughout the world, and this trend will continue for the foreseeable future. The potential to offset the social, economic, and ...
    • Neuron-specific protein interactions of Drosophila CASK-β are revealed by mass spectrometry 

      Mukherjee, Konark; Slawson, Justin B.; Christmann, Bethany L.; Griffith, Leslie C. (Frontiers, 2014-06-30)
      Modular scaffolding proteins are designed to have multiple interactors. CASK, a member of the membrane-associated guanylate kinase (MAGUK) superfamily, has been shown to have roles in many tissues, including neurons and ...
    • Neuronal Na+ Channels Are Integral Components of Pro-Arrhythmic Na+/Ca2+ Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-Adrenergic Stimulation 

      Radwański, Przemysław B.; Ho, Hsiang-Ting; Veeraraghavan, Rengasayee; Brunello, Lucia; Liu, Bin; Belevych, Andriy E.; Unudurthi, Sathya D.; Makara, Michael A.; Priori, Silvia G.; Volpe, Pompeo; Armoundas, Antonis A.; Dillmann, Wolfgang H.; Knollman, Björn C.; Mohler, Peter J.; Hund, Thomas J.; Gyorke, Sandor (Elsevier, 2016-06)
      Although triggered arrhythmias including catecholaminergic polymorphic ventricular tachycardia (CPVT) are often caused by increased levels of circulating catecholamines, the mechanistic link between β-adrenergic receptor ...
    • Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions 

      Kaneko, Kentaro; Xu, Pingwen; Cordonier, Elizabeth L.; Chen, Siyu S.; Ng, Amy; Xu, Yong; Morozov, Alexei; Fukuda, Makoto (Elsevier, 2016-09-13)
      The CNS contributes to obesity and metabolic disease; however, the underlying neurobiological pathways remain to be fully established. Here, we show that the small GTPase Rap1 is expressed in multiple hypothalamic nuclei ...
    • New approaches to investigating social gestures in autism spectrum disorder 

      Kishida, Kenneth T.; Li, Jian; Schwind, Justin; Montague, P. Read (BMC, 2012-05-24)
      The combination of economic games and human neuroimaging presents the possibility of using economic probes to identify biomarkers for quantitative features of healthy and diseased cognition. These probes span a range of ...
    • NLRX1 Is a Multifaceted and Enigmatic Regulator of Immune System Function 

      Nagai-Singer, Margaret A.; Morrison, Holly A.; Allen, Irving C. (2019-10-11)
      Over the last decade, significant progress has been achieved in defining mechanisms underlying NLR regulation of immune system function. However, several NLR family members continue to defy our best attempts at characterization ...
    • Non-Cell Autonomous Roles for CASK in Optic Nerve Hypoplasia 

      Kerr, Alicia; Patel, Paras A.; LaConte, Leslie E.W.; Liang, Chen; Chen, Ching-Kang; Shah, Veeral; Fox, Michael A.; Mukherjee, Konark (ARVO, 2019)
      PURPOSE. Heterozygous mutations in the essential X-linked gene CASK associate with optic nerve hypoplasia (ONH) and other retinal disorders in girls. CASKþ/ heterozygous knockout mice with mosaic CASK expression exhibit ...
    • A novel frequency analysis method for assessing K(ir)2.1 and Na (v)1.5 currents. 

      Rigby, JR; Poelzing, S (2012-04)
      Voltage clamping is an important tool for measuring individual currents from an electrically active cell. However, it is difficult to isolate individual currents without pharmacological or voltage inhibition. Herein, we ...