Now showing items 1-3 of 3

    • Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress 

      Gilmore, Brian L.; Liang, Yanping; Winton, Carly E.; Patel, Kaya; Karageorge, Vasilea; Varano, A. Cameron; Dearnaley, Wwilliam; Sheng, Zhi; Kelly, Deborah F. (Nature Publishing Group, 2017-03-06)
      The precise manner in which physical changes to the breast cancer susceptibility protein (BRCA1) affect its role in DNA repair events remain unclear. Indeed, cancer cells harboring mutations in BRCA1 suffer from genomic ...
    • Structural analysis of BRCA1 reveals modification hotspot 

      Liang, Yanping; Dearnaley, William J.; Varano, A. Cameron; Winton, Carly E.; Gilmore, Brian L.; Alden, Nick A..; Sheng, Zhi; Kelly, Deborah F. (Amer Assoc Advancement Science, 2017-09-01)
    • Visualizing virus particle mobility in liquid at the nanoscale 

      Varano, A. Cameron; Rahimi, Amina; Dukes, Madeline J.; Poelzing, Steven; McDonald, Sarah M.; Kelly, Deborah F. (The Royal Society of Chemistry, 2015-09-04)
      Currently, there remains a critical need to develop real-time imaging resources for life sciences. Here, we demonstrate the use of high resolution in situ imaging to observe biological complexes in liquid at the nanoscale. ...