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Belief about nicotine selectively modulates value and reward prediction error signals in smokers
Little is known about how prior beliefs impact biophysically described processes in the presence of neuroactive drugs, which presents a profound challenge to the understanding of the mechanisms and treatments of addiction. ...
Belief about nicotine modulates subjective craving and insula activity in deprived smokers
Little is known about the specific neural mechanisms through which cognitive factors influence craving and associated brain responses, despite the initial success of cognitive therapies in treating drug addiction. In this ...
Choosing Money over Drugs: The Neural Underpinnings of Difficult Choice in Chronic Cocaine Users
Addiction is considered a disorder that drives individuals to choose drugs at the expense of healthier alternatives. However, chronic cocaine users (CCUs)who meet addiction criteria retain the ability to choose money in ...
BOLD responses to negative reward prediction errors in human habenula
Although positive reward prediction error, a key element in learning that is signaled by dopamine cells, has been extensively studied, little is known about negative reward prediction errors in humans. Detailed animal ...