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Survival kinase genes present prognostic significance in glioblastoma
(Impact Journals Llc, 2016-04-12)
Cancer biomarkers with a strong predictive power for diagnosis/prognosis and a potential to be therapeutic targets have not yet been fully established. Here we employed a loss-of-function screen in glioblastoma (GBM), an ...
Patient-derived glioblastoma stem cells respond differentially to targeted therapies
(Impact Journals Llc, 2016-12-27)
The dismal prognosis of glioblastoma is, at least in part, attributable to the difficulty in eradicating glioblastoma stem cells (GSCs). However, whether this difficulty is caused by the differential responses of GSCs to ...