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Using fMRI to Study Valuation and Choice
(InTech Open, 2014-05-31)
The ability to make decisions relies on brain mechanisms designed to value our environment and elicit appropriate actions based on those values. These mechanisms allow an agent to predict the value of a potential action ...
Randomized Manipulation of Early Cognitive Experience Impacts Adult Brain Structure
(Massachusetts Institute of Technology, 2021)
Does early exposure to cognitive and linguistic stimulation impact brain structure? Or do genetic predispositions account for the co-occurrence of certain neuroanatomical phenotypes and a tendency to engage children in ...
New approaches to investigating social gestures in autism spectrum disorder
(BMC, 2012-05-24)
The combination of economic games and human neuroimaging presents the possibility of using economic probes to identify biomarkers for quantitative features of healthy and diseased cognition. These probes span a range of ...
Irrational exuberance and neural crash warning signals during endogenous experimental market bubbles
(NAS, 2014-07-22)
Groups of humans routinely misassign value to complex future events, especially in settings involving the exchange of resources. If properly structured, experimental markets can act as excellent probes of human group-level ...
Human substantia nigra and ventral tegmental area involvement in computing social error signals during the ultimatum game
(Oxford University Press, 2017-08-17)
As models of shared expectations, social norms play an essential role in our societies. Since our social environment is changing constantly, our internal models of it also need to change. In humans, there is mounting ...
Subsecond dopamine fluctuations in human striatum encode superposed error signals about actual and counterfactual reward
(NAS, 2016-01-05)
In the mammalian brain, dopamine is a critical neuromodulator whose actions underlie learning, decision-making, and behavioral control. Degeneration of dopamine neurons causes Parkinson’s disease, whereas dysregulation of ...
Computational Phenotyping of Two-Person Interactions Reveals Differential Neural Response to Depth-of-Thought
(Public Library of Science, 2012-12-27)
Reciprocating exchange with other humans requires individuals to infer the intentions of their partners. Despite the importance of this ability in healthy cognition and its impact in disease, the dimensions employed and ...
Necessary, Yet Dissociable Contributions of the Insular and Ventromedial Prefrontal Cortices to Norm Adaptation: Computational and Lesion Evidence in Humans
(Society for Neuroscience, 2015-01-14)
Social norms and their enforcement are fundamental to human societies. The ability to detect deviations from norms and to adapt to norms in a changing environment is therefore important to individuals’ normal social ...
Short-term mindfulness practice attenuates reward prediction errors signals in the brain
(Nature Research, 2019-05-06)
Activity changes in dopaminergic neurons encode the ongoing discrepancy between expected and actual value of a stimulus, providing a teaching signal for a reward prediction process. Previous work comparing a cohort of ...
Sub-second Dopamine and Serotonin Signaling in Human Striatum during Perceptual Decision-Making
(CellPress, 2020-12-09)
Recent animal research indicates that dopamine and serotonin, neuromodulators traditionally linked to appetitive and aversive processes, are also involved in sensory inference and decisions based on such inference. We ...