Now showing items 1-10 of 41
The Latent Structure of Interpersonal Problems: Validity of Dimensional, Categorical, and Hybrid Models
(American Psychological Association, 2019-11-01)
Interpersonal problems are key transdiagnostic constructs in psychopathology. In the past, investigators have neglected the importance of operationalizing interpersonal problems according to their latent structure by using ...
Choice bundling, unpacked: Predicted and observed effects on intertemporal choice in an additive model of hyperbolic delay discounting
One method known to increase preference for larger, later rewards (LLRs) over smaller, sooner rewards (SSRs) is choice bundling, in which a single choice produces a series of repeating consequences over time. The present ...
Triangulating abuse liability assessment for flavoured cigar products using physiological, behavioural economic and subjective assessments: a within-subjects clinical laboratory protocol
Introduction In the USA, Food and Drug Administration regulations prohibit the sale of flavoured cigarettes, with menthol being the exception. However, the manufacture, advertisement and sale of flavoured cigar products ...
Dosing parameters for the effects of high-frequency transcranial magnetic stimulation on smoking cessation: Study protocol for a randomized factorial sham-controlled clinical trial
Background: Despite the considerable success of comprehensive tobacco control efforts, tobacco use remains one of the greatest preventable causes of death and disease today. Over half of all smokers in the US make quit ...
Using a human factors-centric approach to development and testing of a face shield designed for health care workers: A COVID-19 case study for process and outcomes
Background: Face shields are a critical piece of personal protective equipment and their comfort impacts compliant use and thus protectiveness. Optimal design criteria for face shield use in healthcare environments are ...
Adenovirus transduction to express human ACE2 causes obesity-specific morbidity in mice, impeding studies on the effect of host nutritional status on SARS-CoV-2 pathogenesis
The COVID-19 pandemic has paralyzed the global economy and resulted in millions of deaths globally. People with co-morbidities like obesity, diabetes and hypertension are at an increased risk for severe COVID-19 illness. ...
Survival of a male patient harboring CASK Arg27Ter mutation to adolescence
Background: CASK is an X-linked gene in mammals and its deletion in males is incompatible with life. CASK heterozygous mutations in female patients associate with intellectual disability, microcephaly, pontocerebellar ...
PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases
Purpose: To establish the relationship between common mutations in the MAPK and PI3K signaling pathways and local progression after radioembolization. Materials and methods: Retrospective review of a HIPAA-compliant ...
Rapid effect of suvorexant and high-dose melatonin on COVID-19 associated delirium
Habitual daily intake of a sweet and fatty snack modulates reward processing in humans
Western diets rich in fat and sugar promote excess calorie intake and weight gain; however, the underlying mechanisms are unclear. Despite a well-documented association between obesity and altered brain dopamine function, ...