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Human substantia nigra and ventral tegmental area involvement in computing social error signals during the ultimatum game
(Oxford University Press, 2017-08-17)
As models of shared expectations, social norms play an essential role in our societies. Since our social environment is changing constantly, our internal models of it also need to change. In humans, there is mounting ...
Belief about nicotine modulates subjective craving and insula activity in deprived smokers
(Frontiers, 2016-07-13)
Little is known about the specific neural mechanisms through which cognitive factors influence craving and associated brain responses, despite the initial success of cognitive therapies in treating drug addiction. In this ...
A computational approach to “free will” constrained by the games we play
(Frontiers, 2012-09-27)
Human choice is not free—we are bounded by a multitude of biological constraints. Yet, within the various landscapes we face, we do express choice, preference, and varying degrees of so-called willful behavior. Moreover, ...
Belief about nicotine selectively modulates value and reward prediction error signals in smokers
(NAS, 2015-02-24)
Little is known about how prior beliefs impact biophysically described processes in the presence of neuroactive drugs, which presents a profound challenge to the understanding of the mechanisms and treatments of addiction. ...
BOLD responses to negative reward prediction errors in human habenula
(Frontiers, 2010-05-11)
Although positive reward prediction error, a key element in learning that is signaled by dopamine cells, has been extensively studied, little is known about negative reward prediction errors in humans. Detailed animal ...
Neural computations underlying social risk sensitivity
(Frontiers, 2012-08-02)
Under standard models of expected utility, preferences over stochastic events are assumed to be independent of the source of uncertainty. Thus, in decision-making, an agent should exhibit consistent preferences, regardless ...
In Cocaine Dependence, Neural Prediction Errors During Loss Avoidance Are Increased With Cocaine Deprivation and Predict Drug Use
(Elsevier, 2018-08-03)
Background: In substance-dependent individuals, drug deprivation and drug use trigger divergent behavioral responses to environmental cues. These divergent responses are consonant with data showing that short- and long-term ...
Longitudinal link between trait motivation and risk-taking behaviors via neural risk processing
(2019-12)
Prior research has emphasized the importance of the motivational system in risky decision-making, yet the mechanisms through which individual differences in motivation may influence adolescents' risk-taking behaviors remain ...
Aging into Perceptual Control: A Dynamic Causal Modeling for fMRI Study of Bistable Perception
(Frontiers, 2016-03-31)
Aging is accompanied by stereotyped changes in functional brain activations, for example a cortical shift in activity patterns from posterior to anterior regions is one hallmark revealed by functional magnetic resonance ...
Opponent Effects of Hyperarousal and Re-experiencing on Affective Habituation in Posttraumatic Stress Disorder
(2020-02)
BACKGROUND: Aberrant emotion processing is a hallmark of posttraumatic stress disorder (PTSD), with neurobiological models suggesting both heightened neural reactivity and diminished habituation to aversive stimuli. However, ...