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Neural masses and fields in dynamic causal modeling
(Frontiers, 2013-05-28)
Dynamic causal modeling (DCM) provides a framework for the analysis of effective connectivity among neuronal subpopulations that subtend invasive (electrocorticograms and local field potentials) and non-invasive ...
Development of NMDAR Antagonists with Reduced Neurotoxic Side Effects: a Study on GK11
(PLOS, 2013-11-19)
The NMDAR glutamate receptor subtype mediates various vital physiological neuronal functions. However, its excessive activation contributes to neuronal damage in a large variety of acute and chronic neurological disorders. ...
Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes
(Elsevier Inc., 2018-11-26)
The data presented pertain to a research article titled “Heme Oxygenase 1 Up-Regulates Glomerular Decay Accelerating Factor Expression and Minimizes Complement Deposition and Injury” (Detsika et al., 2016). The present ...
Gene expression patterns in visual cortex during the critical period: Synaptic stabilization and reversal by visual deprivation
(National Academy of Sciences, 2008-07)
The mapping of eye-specific, geniculocortical inputs to primary visual cortex (V1) is highly sensitive to the balance of correlated activity between the two eyes during a restricted postnatal critical period for ocular ...
Weekly Doxorubicin Increases Coronary Arteriolar Wall and Adventitial Thickness
(PLOS, 2013-02-21)
Background
Doxorubicin (DOX) is associated with premature cardiovascular events including myocardial infarction. This study was performed to determine if the weekly administration of DOX influenced coronary arteriolar ...
Delayed Degradation and Impaired Dendritic Delivery of Intron-Lacking EGFP-Arc/Arg3.1 mRNA in EGFP-Arc Transgenic Mice
(Frontiers, 2018-01-31)
Arc is a unique immediate early gene (IEG) whose expression is induced as synapses are modified during learning. Newly-synthesized ArcmRNA is rapidly transported throughout dendrites and localizes near recently activated ...
Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients
(Frontiers, 2011-10-04)
Experimental data indicates that soluble vascular endothelial growth factor (VEGF) receptor 1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by VEGF-A. To better delineate the role of sFlt-1 in ...
Low Dose Infliximab for Prevention of Postoperative Recurrence of Crohn's Disease: Long Term Follow-Up and Impact of Infliximab Trough Levels and Antibodies to Infliximab
(PLOS, 2015-12-15)
Objective
In patients with postoperative recurrence of Crohn’s disease endoscopic and clinical remission can be maintained for up to 1 year with low infliximab doses (3 mg/Kg). However, in theory low-dose infliximab ...
Dynamic Causal Models and Physiological Inference: A Validation Study Using Isoflurane Anaesthesia in Rodents
(PLOS, 2011)
Generative models of neuroimaging and electrophysiological data present new opportunities for accessing hidden or latent brain states. Dynamic causal modeling (DCM) uses Bayesian model inversion and selection to infer the ...
Utility of Real-Time PCR for Detection of Exserohilum rostratum in Body and Tissue Fluids during the Multistate Outbreak of Fungal Meningitis and Other Infections
(American Society for Microbiology, 2015)
Exserohilum rostratum was the major cause of the multistate outbreak of fungal meningitis linked to contaminated injections of methylprednisolone acetate produced by the New England Compounding Center. Previously, we ...