Now showing items 1-10 of 173
Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes
Arc is a unique immediate early gene whose expression is induced as synapses are being modified during learning. The uniqueness comes from the fact that newly synthesized Arc mRNA is rapidly transported throughout dendrites ...
Diffuse Gastric Ganglioneuromatosis: Novel Presentation of PTEN Hamartoma Syndrome—Case Report and Review of Gastric Ganglioneuromatous Proliferations and a Novel PTEN Gene Mutation
Gastrointestinal ganglioneuromatous proliferations are rare, most often found in the colon, and are three types: polypoid ganglioneuromas, ganglioneuromatous polyposis, and diffuse ganglioneuromatosis. We present a case ...
Mucosal Airway Laceration Secondary To Endobronchial Ultrasonography
Endobronchial ultrasound-guided transbronchial needle aspiration is becoming the standard of care for mediastinal sampling to diagnose and stage lung cancer. It is considered to be safe and rivals the gold standard, ...
Alterations in Brain Connectivity Underlying Beta Oscillations in Parkinsonism
Cortico-basal ganglia-thalamocortical circuits are severely disrupted by the dopamine depletion of Parkinson’s disease (PD), leading to pathologically exaggerated beta oscillations. Abnormal rhythms, found in several circuit ...
Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients
Experimental data indicates that soluble vascular endothelial growth factor (VEGF) receptor 1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by VEGF-A. To better delineate the role of sFlt-1 in ...
BDNF Val(66)Met Polymorphism Influences Visuomotor Associative Learning and the Sensitivity to Action Observation
(Springer Nature, 2016-10-05)
Motor representations in the human mirror neuron system are tuned to respond to specific observed actions. This ability is widely believed to be influenced by genetic factors, but no study has reported a genetic variant ...
Heart Rate and Extracellular Sodium and Potassium Modulation of Gap Junction Mediated Conduction in Guinea Pigs
(Frontiers Media Sa, 2016-02-02)
A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease
(Springer Nature, 2015-09-23)
We present a new molecular toolkit to investigate protein assemblies natively formed in the context of human disease. The system employs tunable microchips that can be decorated with switchable adaptor molecules to select ...
Single Center Retrospective Analysis of Conventional and Radial TIG Catheters for Transradial Diagnostic Coronary Angiography
Current guidelines favor the radial approach for coronary angiography. Therefore, specialty radial diagnostic catheters were designed to engage both coronary arteries with a single device. However, it is unclear if single ...