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RNA sequencing and proteomics approaches reveal novel deficits in the cortex ofMecp2-deficient mice, a model for Rett syndrome.
(2017)
BACKGROUND: Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutations in the transcriptional regulator MeCP2. Much of our understanding of MeCP2 function is derived from transcriptomic studies with ...