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Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients

Hashambhoy, Yasmin L.; Chappell, John C.; Peirce, Shayn M.; Bautch, Victoria L.; Gabhann, Feilim Mac (Frontiers, 2011-10-04)

Experimental data indicates that soluble vascular endothelial growth factor (VEGF) receptor 1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by VEGF-A. To better delineate the role of sFlt-1 in ...