Research articles, presentations, and other scholarship

Recent Submissions

  • Functional and cognitive status in Clostridium difficile infection in the hospitalized elderly: A Retrospective Study of Two Sites 

    Fernandez-Cotarelo, Maria-Jose; Nagy-Agren, Stephanie E.; Smolkin, Mark E.; Jiminez-Diez-Canseco, Leticia; Perez-Pomata, Maria-Teresa; Shenal, Brian V.; Warren, Cirle A. (Springer, 2019-03-20)
    Advanced age is a risk factor for Clostridium difficile infection (CDI), and older patients have more severe CDI and worse outcome [1-3]. We investigated whether CDI in the elderly is associated with functional and cognitive ...
  • Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice 

    Catanzaro, Kelly C. Freudenberger; Champion, Anna E.; Mohapatra, Nrusingh; Cecere, Thomas; Inzana, Thomas J. (Frontiers, 2017-05-30)
    Francisella tularensis is a Gram-negative bacterium and the etiologic agent of tularemia. F. tularensis may appear encapsulated when examined by transmission electron microscopy (TEM), which is due to production of an ...
  • Comparative Genomics and Proteomic Analysis of Assimilatory Sulfate Reduction Pathways in Anaerobic Methanotrophic Archaea 

    Yu, Hang; Susanti, Dwi; McGlynn, Shawn E.; Skennerton, Connor T.; Chourey, Karuna; Iyer, Ramsunder; Scheller, Silvan; Tavormina, Patricia L.; Hettich, Robert L.; Mukhopadhyay, Biswarup; Orphan, Victoria J. (Frontiers, 2018-12-03)
    Sulfate is the predominant electron acceptor for anaerobic oxidation of methane (AOM) in marine sediments. This process is carried out by a syntrophic consortium of anaerobic methanotrophic archaea (ANME) and sulfate ...
  • Neuroimaging Strategies Addressing Challenges in Using fMRI for the Children with Cerebral Palsy 

    Lee-Park, Juniper J.; Deshpande, Harshawardhan; Lisinski, Jonathan; LaConte, Stephen; Ramey, Sharon; DeLuca, Stephanie C. (Scientific Research Publishing Inc., 2018-05-17)
    Aim: This study sought to develop a process and methodology that could be a useful clinical and research tool for successfully completing functional magnetic resonance imaging (fMRI) scanning in children with Cerebral ...
  • A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease 

    Gilmore, Brian L.; Winton, Carly E.; Demmert, Andrew C.; Tanner, Justin R.; Bowman, Sam; Karageorge, Vasilea; Patel, Kaya; Sheng, Zhi; Kelly, Deborah F. (Springer Nature, 2015-09-23)
    We present a new molecular toolkit to investigate protein assemblies natively formed in the context of human disease. The system employs tunable microchips that can be decorated with switchable adaptor molecules to select ...
  • Transudative chylothorax in a patient with lymphangioleiomyomatosis 

    Noriega Aldave, Adrian Pedro; Leslie, John W. (Elsevier, 2017-09-30)
    Transudative chylothorax is a rare type of pleural effusion. It has been described to be present in the setting of liver cirrhosis, heart failure, amyloidosis, nephrotic syndrome, superior vena cava thrombosis, sclerosing ...
  • BDNF Val(66)Met Polymorphism Influences Visuomotor Associative Learning and the Sensitivity to Action Observation 

    Taschereau-Dumouchel, Vincent; Hetu, Sebastien; Michon, Pierre-Emmanuel; Vachon-Presseau, Etienne; Massicotte, Elsa; De Beaumont, Louis; Fecteau, Shirley; Poirier, Judes; Mercier, Catherine; Chagnon, Yvon C.; Jackson, Philip L. (Springer Nature, 2016-10-05)
    Motor representations in the human mirror neuron system are tuned to respond to specific observed actions. This ability is widely believed to be influenced by genetic factors, but no study has reported a genetic variant ...
  • Circadian dynamics in measures of cortical excitation and inhibition balance 

    Chellappa, Sarah L.; Gaggioni, Giulia; Ly, Julien Q. M.; Papachilleos, Soterios; Borsu, Chloe; Brzozowski, Alexandre; Rosanova, Mario; Sarasso, Simone; Luxen, Andre; Middleton, Benita; Archer, Simon N.; Dijk, Derk-Jan; Massimini, Marcello; Maquet, Pierre; Phillips, Christophe; Moran, Rosalyn J.; Vandewalle, Gilles (Springer Nature, 2016-09-21)
    Several neuropsychiatric and neurological disorders have recently been characterized as dysfunctions arising from a 'final common pathway' of imbalanced excitation to inhibition within cortical networks. How the regulation ...
  • Clinical Management of Low Vitamin D: A Scoping Review of Physician's Practices 

    Rockwell, Michelle; Kraak, Vivica; Hulver, Matthew; Epling, John (MDPI, 2018-04-16)
    The role of vitamin D in the prevention and treatment of non-skeletal health issues has received significant media and research attention in recent years. Costs associated with clinical management of low vitamin D (LVD) ...
  • Implications of Probiotics on the Maternal-Neonatal Interface: Gut Microbiota, Immunomodulation, and Autoimmunity 

    Swartout, Brianna; Luo, Xin M. (Frontiers, 2018-12-03)
    Probiotics are being investigated for the treatment of autoimmune disease by re-balancing dysbiosis induced changes in the immune system. Pregnancy is a health concern surrounding autoimmune disease, both for the mother ...
  • Implantable strain sensor to monitor fracture healing with standard radiography 

    Pelham, Hunter; Benza, Donald; Millhouse, Paul W.; Carrington, Nathan; Arifuzzaman, Md.; Behrend, Caleb J.; Anker, Jeffrey N.; DesJardins, John D. (Springer Nature, 2017-05-04)
    Current orthopaedic clinical methods do not provide an objective measure of fracture healing or weight bearing for lower extremity fractures. The following report describes a novel approach involving in-situ strain sensors ...
  • Genetic determinants restricting the reassortment of heterologous NSP2 genes into the simian rotavirus SA11 genome 

    Mingo, Rebecca; Zhang, Shu; Long, Courtney P.; LaConte, Leslie E. W.; McDonald, Sarah M. (Springer Nature, 2017-08-24)
    Rotaviruses (RVs) can evolve through the process of reassortment, whereby the 11 double-stranded RNA genome segments are exchanged among strains during co-infection. However, reassortment is limited in cases where the genes ...
  • Cell Cycle Model System for Advancing Cancer Biomarker Research 

    Lazar, Iulia M.; Hoeschele, Ina; de Morais, Juliana; Tenga, Milagros J. (Springer Nature, 2017-12-21)
    Progress in understanding the complexity of a devastating disease such as cancer has underscored the need for developing comprehensive panels of molecular markers for early disease detection and precision medicine applications. ...
  • Early childhood investment impacts social decision-making four decades later 

    Luo, Yi; Hetu, Sebastien; Lohrenz, Terry; Hula, Andreas; Dayan, Peter; Ramey, Sharon Landesman; Sonnier-Netto, Libbie; Lisinski, Jonathan; LaConte, Stephen; Nolte, Tobias; Fonagy, Peter; Rahmani, Elham; Montague, P. Read; Ramey, Craig (Nature Research, 2018-11-20)
    Early childhood educational investment produces positive effects on cognitive and non-cognitive skills, health, and socio-economic success. However, the effects of such interventions on social decision-making later in life ...
  • Monte Carlo Planning Method Estimates Planning Horizons during Interactive Social Exchange 

    Hula, Andreas; Montague, P. Read; Dayan, Peter (PLOS, 2015-06)
    Reciprocating interactions represent a central feature of all human exchanges. They have been the target of various recent experiments, with healthy participants and psychiatric populations engaging as dyads in multi-round ...
  • Modulation of CREB in the Dorsal Lateral Geniculate Nucleus of Dark-Reared Mice 

    Krahe, Thomas E.; Seabrook, Tania A.; Chen, Ching Kang J.; Fox, Michael A.; Guido, William (Hindawi, 2012)
    The cAMP-response element-binding protein (CREB) plays an important role in visual cortical plasticity that follows the disruption of sensory activity, as induced by dark rearing (DR). Recent findings indicate that the ...
  • Nuclei-specific differences in nerve terminal distribution, morphology, and development in mouse visual thalamus 

    Hammer, Sarah; Carrillo, Gabriela; Govindaiah, Gubbi; Monavarfeshani, Aboozar; Bircher, Joseph S.; Su, Jianmin; Guido, William; Fox, Michael A. (BMC, 2014)
    Background: Mouse visual thalamus has emerged as a powerful model for understanding the mechanisms underlying neural circuit formation and function. Three distinct nuclei within mouse thalamus receive retinal input, the ...
  • Developmental remodeling of relay cells in the dorsal lateral geniculate nucleus in the absence of retinal input 

    El-Danaf, Rana N.; Krahe, Thomas E.; Dilger, Emily K.; Bickford, Martha E.; Fox, Michael A.; Guide, William (BMC, 2015)
    Background: The dorsal lateral geniculate nucleus (dLGN) of the mouse has been an important experimental model for understanding thalamic circuit development. The developmental remodeling of retinal projections has been ...
  • Inflammatory demyelination alters subcortical visual circuits 

    Araújo, Sheila Espírito; Mendonça, Henrique Rocha; Wheeler, Natalie A.; Campello-Costa, Paula; Jacobs, Kimberle M.; Gomes, Flávia C.A.; Fox, Michael A.; Fuss, Babette (BMC, 2017)
    Background: Multiple sclerosis (MS) is an inflammatory demyelinating disease classically associated with axonal damage and loss; more recently, however, synaptic changes have been recognized as additional contributing ...
  • Agrin and Synaptic Laminin Are Required to Maintain Adult Neuromuscular Junctions 

    Samuel, Melanie; Valdez, Gregorio; Tapia, Juan C.; Lichtman, Jeff W.; Sanes, Joshua R. (PLOS, 2012-10-03)
    As synapses form and mature the synaptic partners produce organizing molecules that regulate each other’s differentiation and ensure precise apposition of pre- and post-synaptic specializations. At the skeletal neuromuscular ...

View more