Now showing items 1-20 of 160

    • Heat transfer model to characterize the focal cooling necessary to suppress spontaneous epileptiform activity 

      Guerra, Reynaldo G.; Davalos, Rafael V.; Garcia, Paul A.; Rubinsky, Boris; Berger, Mitchel (SPIE, 2005-04-14)
      Epilepsy is characterized by paroxysmal transient disturbances of the electrical activity of the brain. Symptoms are manifested as impairment of motor, sensory, or psychic function with or without loss of consciousness or ...
    • Effects of receptor clustering on ligand dissociation kinetics: Theory and simulations 

      Gopalakrishnan, Mahima; Forsten-Williams, K.; Nugent, M. A.; Täuber, Uwe C. (CELL PRESS, 2005-12-01)
      Receptor-ligand binding is a critical first step in signal transduction and the duration of the interaction can impact signal generation. In mammalian cells, clustering of receptors may be facilitated by heterogeneous zones ...
    • Mathematical Study and Numerical Simulation of Multispectral Bioluminescence Tomography 

      Han, Weimin; Cong, Wenxiang; Wang, Ge (Hindawi, 2006-12-12)
      Multispectral bioluminescence tomography (BLT) attracts increasinglymore attention in the area of optical molecular imaging. In this paper, we analyzethe properties of the solutions to the regularized and discretized ...
    • Canine Cancer Screening Via Ultraviolet Absorbance And Fluorescence Spectroscopy Of Serum Proteins 

      Dickerson, Bryan Douglas; Geist, Brian L.; Spillman, William B. Jr.; Robertson, John L. (Optical Society of America, 2007-01-01)
      A cost-effective optical cancer screening and monitoring technique was demonstrated in a pilot study of canine serum samples and was patented for commercialization. Compared to conventional blood chemistry analysis methods, ...
    • A General Local Reconstruction Approach Based on a Truncated Hilbert Transform 

      Ye, Yangbo; Yu, Hengyong; Wei, Yuchuan; Wang, Ge (Hindawi, 2007-06-17)
      Exact image reconstruction from limited projection data has been a central topic in the computed tomography (CT) field. In this paper, we present a general region-of-interest/volume-of-interest (ROI/VOI) reconstruction ...
    • A Fast CT Reconstruction Scheme for a General Multi-Core PC 

      Zeng, Kai; Bai, Erwei; Wang, Ge (Hindawi, 2007-07-04)
      Expensive computational cost is a severe limitation in CT reconstruction for clinical applications that need real-time feedback. A primary example is bolus-chasing computed tomography (CT) angiography (BCA) that we have ...
    • Mathematical Modeling of Irreversible Electroporation for Treatment Planning 

      Edd, Jon F.; Davalos, Rafael V. (Sage, 2007-08)
      Irreversible Electroporation (IRE) is a new drug-free method to ablate undesirable tissue of particular use in cancer therapy. IRE achieves cell death within the targeted tissue through a series of electric pulses that ...
    • A General Formula for Fan-Beam Lambda Tomography 

      Yu, Hengyong; Wang, Ge (Hindawi, 2007-08-23)
    • Improving the Accuracy of the Diffusion Model in Highly Absorbing Media 

      Cong, Alexander X.; Shen, Haiou; Cong, Wenxiang; Wang, Ge (Hindawi, 2007-08-29)
      The diffusion approximation of the Boltzmann transport equation is most commonly used for describing the photon propagation in turbid media. It produces satisfactory results in weakly absorbing and highly scattering media, ...
    • Image Reconstruction For Bioluminescence Tomography From Partial Measurement 

      Jiang, M.; Zhou, T.; Cheng, J. T.; Cong, W. X.; Wang, Ge (Optical Society of America, 2007-09-01)
      The bioluminescence tomography is a novel molecular imaging technology for small animal studies. Known reconstruction methods require the completely measured data on the external surface, although only partially measured ...
    • Experimental Study on Bioluminescence Tomography with Multimodality Fusion 

      Lv, Yujie; Tian, Jie; Cong, Wenxiang; Wang, Ge (Hindawi, 2007-09-10)
      To verify the influence of a priori information on the nonuniqueness problem of bioluminescence tomography (BLT), the multimodality imaging fusion based BLT experiment is performed by multiview noncontact detection mode, ...
    • Tumor Ablation with Irreversible Electroporation 

      Al-Sakere, Bassim; Andre, Franck; Bernat, Claire; Connault, Elisabeth; Opolon, Paule; Davalos, Rafael V.; Rubinsky, Boris; Mir, Lluis M. (PLOS, 2007-11-07)
      We report the first successful use of irreversible electroporation for the minimally invasive treatment of aggressive cutaneous tumors implanted in mice. Irreversible electroporation is a newly developed non-thermal tissue ...
    • SBES News, Summer/Fall 2008 

      School of Biomedical Engineering and Sciences (Virginia Tech, 2008)
      This is the annual newsletter for the School of Biomedical Engineering and Sciences.
    • Digital Spectral Separation Methods And Systems For Bioluminescence Imaging 

      Wang, Ge; Shen, Haiou; Liu, Y.; Cong, A.; Cong, W. X.; Wang, Y.; Dubey, P. (Optical Society of America, 2008-01-01)
      We propose a digital spectral separation (DSS) system and methods to extract spectral information optimally from a weak multispectral signal such as in the bioluminescent imaging (BLI) studies. This system utilizes our ...
    • Exact Interior Reconstruction with Cone-Beam CT 

      Ye, Yangbo; Yu, Hengyong; Wang, Ge (Hindawi, 2008-01-23)
      Using the backprojection filtration (BPF) and filtered backprojection (FBP) approaches, respectively, we prove that with cone-beam CT the interior problem can be exactly solved by analytic continuation. The prior knowledge ...
    • Cone-Beam Composite-Circling Scan and Exact Image Reconstruction for a Quasi-Short Object 

      Yu, Hengyong; Wang, Ge (Hindawi, 2008-02-03)
      Here we propose a cone-beam composite-circling mode to solve the quasi-short object problem, which is to reconstruct a short portion of a long object from longitudinally truncated cone-beam data involving the short object. ...
    • X-Ray Phase-Contrast Imaging with Three 2D Gratings 

      Jiang, Ming; Wyatt, Christopher Lee; Wang, Ge (Hindawi, 2008-03-24)
      X-ray imaging is of paramount importance for clinical and preclinical imaging but it is fundamentally restricted by the attenuation-based contrast mechanism, which has remained essentially the same since Roentgen's discovery ...
    • Exact Interior Reconstruction from Truncated Limited-Angle Projection Data 

      Ye, Yangbo; Yu, Hengyong; Wang, Ge (Hindawi, 2008-05-06)
      Using filtered backprojection (FBP) and an analytic continuation approach, we prove that exact interior reconstruction is possible and unique from truncated limited-angle projection data, if we assume a prior knowledge on ...
    • Bioluminescence Tomography - Inner-light, Insight from Infrared 

      Wang, Ge (2008-06-12)
      Bioluminescence tomography (BLT) is a molecular imaging modality, which derives a bioluminescent source distribution inside a small animal from external bioluminescent signals. We published the first paper on BLT in 2004 ...
    • Spiral Cone-beam CT - Successes with Spiral Scans 

      Wang, Ge (2008-06-12)
      X-ray computed tomography (CT) is instrumental in medicine, industry and homeland security, which depicts internal structures of an object from its shadows projected in a fan-beam or cone-beam from an x-ray source along a ...