Browsing Scholarly Works, School of Biomedical Engineering and Sciences by Title
Now showing items 91-110 of 132
-
Opponent Effects of Hyperarousal and Re-experiencing on Affective Habituation in Posttraumatic Stress Disorder
(2020-02)BACKGROUND: Aberrant emotion processing is a hallmark of posttraumatic stress disorder (PTSD), with neurobiological models suggesting both heightened neural reactivity and diminished habituation to aversive stimuli. However, ... -
Optimizing the restored chemotactic behavior of anticancer agent Salmonella enterica serovar Typhimurium VNP20009
(Elsevier, 2017-06-10)Bacteria, including strains of Salmonella, have been researched and applied as therapeutic cancer agents for centuries. Salmonella are particularly of interest due to their facultative anaerobic nature, facilitating ... -
A Parametric Study Delineating Irreversible Electroporation from Thermal Damage Based on a Minimally Invasive Intracranial Procedure
(2011-04-30)Background Irreversible electroporation (IRE) is a new minimally invasive technique to kill undesirable tissue in a non-thermal manner. In order to maximize the benefits from an IRE procedure, the pulse parameters and ... -
Pathology of non-thermal irreversible electroporation (N-TIRE)-induced ablation of the canine brain
(Korean Society of Veterinary Science, 2013-12-01)This study describes the neuropathologic features of normal canine brain ablated with non-thermal irreversible electroporation (N-TIRE). The parietal cerebral cortices of four dogs were treated with N-TIRE using a ... -
Performance enhancement of piezoelectric energy harvesters from wake galloping
(AIP Publishing, 2013-07-01)Experiments are performed to investigate the effects of wake galloping on the range of flow speeds over which a galloping-based piezoaeroelastic energy harvester can be effectively used. Two different upstream cylinders ... -
Predictive therapeutic planning for irreversible electroporation treatment of spontaneous malignant glioma
(Wiley, 2017-07-25)Purpose: Irreversible electroporation (IRE) has been developed as a promising minimally invasive treatment to ablate spontaneous brain tumors with pulsed electric fields in canine patients. The purpose of the study is to ... -
Preferred Placement and Usability of a Smart Textile System vs. Inertial Measurement Units for Activity Monitoring
(MDPI, 2018-08-01)Wearable sensors and systems have become increasingly popular in recent years. Two prominent wearable technologies for human activity monitoring are smart textile systems (STSs) and inertial measurement units (IMUs). Despite ... -
Pulsed Ultrasound Differentially Stimulates Somatosensory Circuits in Humans as Indicated by EEG and fMRI
(PLOS, 2012-12-04)Peripheral somatosensory circuits are known to respond to diverse stimulus modalities. The energy modalities capable of eliciting somatosensory responses traditionally belong to mechanical, thermal, electromagnetic, and ... -
Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores
(Springer Nature, 2016-07-07)5-hydroxymethylcytosine (5 hmC), the oxidized form of 5-methylcytosine (5 mC), is a base modification with emerging importance in biology and disease. However, like most epigenetic elements, it is transparent to many ... -
Rapid Stereomicroscopic Imaging of HER2 Overexpression in Ex Vivo Breast Tissue Using Topically Applied Silica-Based Gold Nanoshells
(Hindawi, 2012-10-22)Tumor margin detection for patients undergoing breast conservation surgery primarily occurs postoperatively. Previously, we demonstrated that gold nanoshells rapidly enhance contrast of HER2 overexpression in ex vivo tissue ... -
Real-time prediction of patient immune cell modulation during irreversible electroporation therapy
(2019-11-28)Immunotherapies have demonstrated limited efficacy in pancreatic ductal adenocarcinoma (PDAC) patients despite their success in treating other tumor types. This limitation is largely due to the relatively immunosuppressive ... -
SART-Type Image Reconstruction from a Limited Number of Projections with the Sparsity Constraint
(Hindawi, 2010-04-26)Based on the recent mathematical findings on solving the linear inverse problems with sparsity constraints by Daubechiesx et al., here we adapt a simultaneous algebraic reconstruction technique (SART) for image reconstruction ... -
SART-Type Image Reconstruction from Overlapped Projections
(Hindawi, 2010-09-05)To maximize the time-integrated X-ray flux from multiple X-ray sources and shorten the data acquisition process, a promising way is to allow overlapped projections from multiple sources being simultaneously on without ... -
Sex Differences in beta-Adrenergic Responsiveness of Action Potentials and Intracellular Calcium Handling in Isolated Rabbit Hearts
(PLOS, 2014-10-23)Cardioprotection in females, as observed in the setting of heart failure, has been attributed to sex differences in intracellular calcium handling and its modulation by b-adrenergic signaling. However, further studies ... -
Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study
(Springer, 2015-10-01)It has long been held that electrical excitation spreads from cell-to-cell in the heart via low resistance gap junctions (GJ). However, it has also been proposed that myocytes could interact by non-GJ-mediated “ephaptic” ... -
Sphingolipid Metabolites Modulate Dielectric Characteristics of Cells in a Mouse Ovarian Cancer Progression Model
(The Royal Society of Chemistry, 2013-03-27)Currently, conventional cancer treatment regimens often rely upon highly toxic chemotherapeutics or target oncogenes that are variably expressed within the heterogeneous cell population of tumors. These challenges highlight ... -
A Stationary-Sources and Rotating-Detectors Computed Tomography Architecture for Higher Temporal Resolution and Lower Radiation Dose
(IEEE, 2014)In current computed tomography (CT) architecture, both X-ray tubes and X-ray detectors are rotated mechanically around an object to collect a sufficient number of projections. This architecture has been shown to not be ... -
Stochastic optical reconstruction microscopy-based relative localization analysis (STORM-RLA) for quantitative nanoscale assessment of spatial protein organization
(Amer Soc Cell Biology, 2016-11-07)The spatial association between proteins is crucial to understanding how they function in biological systems. Colocalization analysis of fluorescence microscopy images is widely used to assess this. However, colocalization ... -
Structural analysis of BRCA1 reveals modification hotspot
(Amer Assoc Advancement Science, 2017-09-01) -
Successful Treatment of a Large Soft Tissue Sarcoma With Irreversible Electroporation
(American Society of Clinical Oncology, 2011-05-01)Irreversible electroporation (IRE) is a promising technique for the focal treatment of pathologic tissues that involves placing minimally invasive electrodes within the targeted region. A series of short, intense electric ...
