Browsing Scholarly Works, School of Biomedical Engineering and Sciences by Author "Rossmeisl, John H."
Now showing items 1-4 of 4
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High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction
Arena, Christopher B.; Sano, Michael B.; Rossmeisl, John H.; Caldwell, John L.; Garcia, Paulo A.; Rylander, Marissa N.; Davalos, Rafael V. (2011-11-21)Background Therapeutic irreversible electroporation (IRE) is an emerging technology for the non-thermal ablation of tumors. The technique involves delivering a series of unipolar electric pulses to permanently destabilize ... -
High-Frequency Irreversible Electroporation for Intracranial Meningioma: A Feasibility Study in a Spontaneous Canine Tumor Model
Latouche, Eduardo L.; Arena, Christopher B.; Ivey, Jill W.; Garcia, Paulo A.; Pancotto, Theresa E.; Pavlisko, Noah; Verbridge, Scott; Davalos, Rafael V.; Rossmeisl, John H. (Sage, 2018)High-frequency irreversible electroporation is a nonthermal method of tissue ablation that uses bursts of 0.5- to 2.0-microsecond bipolar electric pulses to permeabilize cell membranes and induce cell death. High-frequency ... -
A Parametric Study Delineating Irreversible Electroporation from Thermal Damage Based on a Minimally Invasive Intracranial Procedure
Garcia, Paulo A.; Rossmeisl, John H.; Neal, Robert E. II; Ellis, Thomas L.; Davalos, Rafael V. (2011-04-30)Background Irreversible electroporation (IRE) is a new minimally invasive technique to kill undesirable tissue in a non-thermal manner. In order to maximize the benefits from an IRE procedure, the pulse parameters and ... -
Temporal Characterization of Blood–Brain Barrier Disruption with High-Frequency Electroporation
Lorenzo, Melvin F.; Thomas, Sean C.; Kani, Yukitaka; Hinckley, Jonathan; Lee, Matthew; Adler, Joy; Verbridge, Scott; Hsu, Fang-Chi; Robertson, John L.; Davalos, Rafael V.; Rossmeisl, John H. (MDPI, 2019-11-23)Treatment of intracranial disorders suffers from the inability to accumulate therapeutic drug concentrations due to protection from the blood–brain barrier (BBB). Electroporation-based therapies have demonstrated the ...