Now showing items 1-10 of 10
A Numerical Investigation of the Electric and Thermal Cell Kill Distributions in Electroporation-Based Therapies in Tissue
Electroporation-based therapies are powerful biotechnological tools for enhancing the delivery of exogeneous agents or killing tissue with pulsed electric fields (PEFs). Electrochemotherapy (ECT) and gene therapy based on ...
Predictive therapeutic planning for irreversible electroporation treatment of spontaneous malignant glioma
Purpose: Irreversible electroporation (IRE) has been developed as a promising minimally invasive treatment to ablate spontaneous brain tumors with pulsed electric fields in canine patients. The purpose of the study is to ...
High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction
Background Therapeutic irreversible electroporation (IRE) is an emerging technology for the non-thermal ablation of tumors. The technique involves delivering a series of unipolar electric pulses to permanently destabilize ...
A Parametric Study Delineating Irreversible Electroporation from Thermal Damage Based on a Minimally Invasive Intracranial Procedure
Background Irreversible electroporation (IRE) is a new minimally invasive technique to kill undesirable tissue in a non-thermal manner. In order to maximize the benefits from an IRE procedure, the pulse parameters and ...
Pathology of non-thermal irreversible electroporation (N-TIRE)-induced ablation of the canine brain
(Korean Society of Veterinary Science, 2013-12-01)
This study describes the neuropathologic features of normal canine brain ablated with non-thermal irreversible electroporation (N-TIRE). The parietal cerebral cortices of four dogs were treated with N-TIRE using a ...
A Three-Dimensional in Vitro Tumor Platform for Modeling Therapeutic Irreversible Electroporation
(CELL PRESS, 2012-06-01)
Irreversible electroporation (IRE) is emerging as a powerful tool for tumor ablation that utilizes pulsed electric fields to destabilize the plasma membrane of cancer cells past the point of recovery. The ablated region ...
Successful Treatment of a Large Soft Tissue Sarcoma With Irreversible Electroporation
(American Society of Clinical Oncology, 2011-05-01)
Irreversible electroporation (IRE) is a promising technique for the focal treatment of pathologic tissues that involves placing minimally invasive electrodes within the targeted region. A series of short, intense electric ...
Invited Review-Neuroimaging Response Assessment Criteria for Brain Tumors in Veterinary Patients
Towards the creation of decellularized organ constructs using irreversible electroporation and active mechanical perfusion
(Biomed Central Ltd, 2010-12-10)
High-Frequency Irreversible Electroporation for Intracranial Meningioma: A Feasibility Study in a Spontaneous Canine Tumor Model
High-frequency irreversible electroporation is a nonthermal method of tissue ablation that uses bursts of 0.5- to 2.0-microsecond bipolar electric pulses to permeabilize cell membranes and induce cell death. High-frequency ...