Now showing items 1-10 of 93
Gene Ontology annotation of the rice blast fungus, Magnaporthe oryzae
Background Magnaporthe oryzae, the causal agent of blast disease of rice, is the most destructive disease of rice worldwide. The genome of this fungal pathogen has been sequenced and an automated annotation has recently ...
Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit
(Academic Press Ltd Elsevier Science Ltd, 2008-05-29)
Team Science: 2007 Annual Report
(Virginia Bioinformatics Institute, 2007-01-07)
Plasmids and Rickettsial Evolution: Insight from Rickettsia felis
Background The genome sequence of Rickettsia felis revealed a number of rickettsial genetic anomalies that likely contribute not only to a large genome size relative to other rickettsiae, but also to phenotypic oddities ...
Burst of Young Retrogenes and Independent Retrogene Formation in Mammals
Retroposition and retrogenes gain increasing attention as recent studies show that they play an important role in human new gene formation. Here we examined the patterns of retrogene distribution in 8 mammalian genomes ...
Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly
The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet polymer that alternates two types of lateral ...
An Atlas of the Speed of Copy Number Changes in Animal Gene Families and Its Implications
The notion that gene duplications generating new genes and functions is commonly accepted in evolutionary biology. However, this assumption is more speculative from theory rather than well proven in genome-wide studies. ...
Common themes in nutrient acquisition by plant symbiotic microbes, described by the Gene Ontology
A critical function for symbionts is the acquisition of nutrients from their host. Relationships between hosts and symbionts range from biotrophic mutualism to necrotrophic parasitism, with a corresponding range of structures ...
The Plant-Associated Microbe Gene Ontology (PAMGO) Consortium: community development of new Gene Ontology terms describing biological processes involved in microbe-host interactions
All microbes that form beneficial, neutral, or pathogenic associations with hosts face similar challenges. They must physically adhere to and/or gain entry to host tissues; they must avoid, suppress, or tolerate host ...
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
Background Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, together with a statistical significance ...