Now showing items 1-10 of 143
Multiscale Coupling of Transcranial Direct Current Stimulation to Neuron Electrodynamics: Modeling the Influence of the Transcranial Electric Field on Neuronal Depolarization
(Hindawi Publishing Corporation, 2014-10-23)
Transcranial direct current stimulation (tDCS) continues to demonstrate success as a medical intervention for neurodegenerative diseases, psychological conditions, and traumatic brain injury recovery. One aspect of tDCS ...
e-Connections, vol. 5, no. 2; Summer 2010
(Virginia Bioinformatics Institute, Virginia Tech, 2010-06)
Learning Chemistry from Bacteria
Dr. Jon Clardy Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard University All animals, including humans, originated and evolved on a planet already teeming with bacteria, and ...
Systematic Reverse Engineering of Network Topologies: A Case Study of Resettable Bistable Cellular Responses
(Public Library of Science, 2014-08-29)
A focused theme in systems biology is to uncover design principles of biological networks, that is, how specific network structures yield specific systems properties. For this purpose, we have previously developed a reverse ...
HIV-1 drug discovery: targeting folded RNA structures with branched peptides
(The Royal Society of Chemistry, 2015-04-28)
Human immunodeficiency virus type 1 (HIV-1) is an RNA virus that is prone to high rates of mutation. While the disease is managed with current antiretroviral therapies, drugs with a new mode of action are needed. A strategy ...
The Virginia Bioinformatics Institute 2009 annual report
(Virginia Bioinformatics Institute, 2010-01-05)
PLoS Computational Biology Conference Postcards from PSB 2010
(Public Library of Science, 2010-04-29)
Welcome to PLoS Conference Postcards. Postcards, as the name suggests, are designed to vividly recount to those not at a conference what happened at the event that was scientifically noteworthy and therefore make the reader ...
STRATEGY FOR A NATIONAL COMMUNITY LEARNING NETWORK: COMMUNITY LEARNING DATA DRIVEN DISCOVERY - Building Capacity for Evidence-Based Decision Making
The Social and Decision Analytics Laboratory (SDAL) of the Biocomplexity Institute of Virginia Tech received a planning grant from the Laura and John Arnold Foundation (LJAF) to develop a strategy for a national community ...
What Factors Might Have Led to the Emergence of Ebola in West Africa?
An Ebola outbreak of unprecedented scope emerged in West Africa in December 2013 and presently continues unabated in the countries of Guinea, Sierra Leone, and Liberia. Ebola is not new to Africa, and outbreaks have been ...
A Simulation Optimization Approach to Epidemic Forecasting
Reliable forecasts of influenza can aid in the control of both seasonal and pandemic outbreaks. We introduce a simulation optimization (SIMOP) approach for forecasting the influenza epidemic curve. This study represents ...