Now showing items 1-10 of 248
Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection
Immune responses to Helicobacter pylori are orchestrated through complex balances of host-bacterial interactions, including inflammatory and regulatory immune responses across scales that can lead to the development of the ...
Modeling the Mechanisms by Which HIV Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa
Human immunodeficiency virus (HIV)-infected patients are at an increased risk of co-infection with human papilloma virus (HPV), and subsequent malignancies such as oral cancer. To determine the role of HIV-associated immune ...
Research and Education at the Virginia Bioinformatics Institute at Virginia Tech
Virginia Tech, the largest research university in the Commonwealth of Virginia, has developed over the last 15 years resources essential for high throughput biological and computational research. Using these resources, VT ...
Prediction of Disease and Phenotype Associations from Genome-Wide Association Studies
Background Genome wide association studies (GWAS) have proven useful as a method for identifying genetic variations associated with diseases. In this study, we analyzed GWAS data for 61 diseases and phenotypes to elucidate ...
Modeling Commodity Flow in the Context of Invasive Species Spread: Study of Tuta absoluta in Nepal
(Virginia Tech, 2017)
Trade and transport of goods is widely accepted as a primary pathway for the introduction and dispersal of invasive species. However, understanding commodity flows remains a challenge owing to its complex nature, unavailability ...
Envisioning Our Future: 2011 & 2012 Highlights
(Virginia Bioinformatics Institute, 2012-12-05)
Discovering Networks of Perturbed Biological Processes in Hepatocyte Cultures
The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs and environmental ...