Now showing items 484-503 of 617

    • Rediscovering the King of Woodpeckers: Exploring the Implications 

      Walters, J. R.; Crist, E. L. (Resilience Alliance, 2005-12)
      The Ivory-billed Woodpecker has long held a special place in the psyche of North American conservation, eliciting unusually colorful prose, even from scientists, as an icon of the wild. The reverence in which it was held ...
    • A Regulatory Network for Coordinated Flower Maturation 

      Reeves, Paul H.; Ellis, Christine M.; Ploense, Sara E.; Wu, Miin-Feng; Yadav, Vandana; Tholl, Dorothea; Chetelat, Aurore; Haupt, Ina; Kennerley, Brian J.; Hodgens, Charles; Farmer, Edward E.; Nagpal, Punita; Reed, Jason W. (PLoS, 2012-02)
      For self-pollinating plants to reproduce, male and female organ development must be coordinated as flowers mature. The Arabidopsis transcription factors AUXIN RESPONSE FACTOR 6 (ARF6) and ARF8 regulate this complex process ...
    • The Reluctant Warriors: Scientist vs Public Relations Spin Doctors 

      Cairns, John (Virginia Tech, 2010)
      When scientists listen to analyses of existing evidence, they usually can decipher which analysis is supported by a preponderance of evidence, and if no clear evidence emerges they wait until adequate information is ...
    • Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5 

      Peng, Liang; Zhang, Hui; Hao, Yuanyuan; Xu, Feihong; Yang, Jianjun; Zhang, Ruihua; Lu, Geming; Zheng, Zihan; Cui, Miao; Qi, Chen-Feng; Chen, Chun; Wang, Juan; Hu, Yuan; Wang, Di; Pierce, Susan; Li, Liwu; Xiong, Huabao (2016-12)
      The regulation of macrophage orientation pathological conditions is important but still incompletely understood. Here, we show that IL-10 and Rag1 double knockout mice spontaneously develop colitis with dominant M1 macrophage ...
    • Requiem for the Biosphere 

      Cairns, John (Virginia Tech, 2010)
      Humans, although many are reluctant to admit it, are reliant on the health of the biosphere for their survival. Certain threats to the biosphere are very complex, like biodiversity loss, while others are fairly simple, ...
    • Resident Microbiome Disruption with Antibiotics Enhances Virulence of a Colonizing Pathogen 

      Thomason, Courtney A.; Mullen, Nathan; Belden, Lisa K.; May, Meghan; Hawley, Dana M. (Springer Nature, 2017-11-23)
      There is growing evidence that symbiotic microbes play key roles in host defense, but less is known about how symbiotic microbes mediate pathogen-induced damage to hosts. Here, we use a natural wildlife disease system, ...
    • Restoring Damaged Aquatic Ecosystems 

      Cairns, John (The Journal of Social, Political, and Economic Studies, 2006)
      Aquatic ecosystems must play a major role to ensure that water, which is both essential and scarce, is always available for both present and future generations. This has become even more urgent in light of the ongoing ...
    • Retinal-input-induced epigenetic dynamics in the developing mouse dorsal lateral geniculate nucleus 

      He, Jianlin; Xu, Xiguang; Monavarfeshani, Aboozar; Banerjee, Sharmi; Fox, Michael A.; Xie, Hehuang (2019-02-14)
      Abstract DNA methylation plays important roles in the regulation of nervous system development and in cellular responses to environmental stimuli such as light-derived signals. Despite great efforts in ...
    • The Role of Constructed Ecosystems in an Era of Rapid Culture 

      Cairns, John (Asian Journal of Experimental Sciences, 2007)
      Rapid climate change is causing ecological disequilibrium in many parts of the planet, which makes restoration of natural ecosystems to predisturbance conditions less probable. An alternative to restored ecosystems may be ...
    • The Role of Thyroxine on the Production of Plumage in the American Kestrel (Falco Sparterius) 

      Quinn, Michael J., Jr.; French, John B., Jr.; McNabb, F. M. Anne; Ottinger, Mary Ann (Raptor Research Foundation, 2005)
      In a prior study (Quinn et al. 2002), we examined the effects of Aroclor 1242 (a mixture of polychlorinated biphenyls [PCB]) on feather production in the American Kestrel (Falco sparverius). The development of plumage is ...
    • Role of YpeB in Cortex Hydrolysis during Germination of Bacillus anthracis Spores 

      Bernhards, Casey B.; Popham, David L. (American Society for Microbiology, 2014-07-14)
      The infectious agent of the disease anthrax is the spore of Bacillus anthracis. Bacterial spores are extremely resistant to environmental stresses, which greatly hinders spore decontamination efforts. The spore cortex, a ...
    • A Rootstock Provides Water Conservation for a Grafted Commercial Tomato (Solanum lycopersicum L.) Line in Response to Mild-Drought Conditions: A Focus on Vegetative Growth and Photosynthetic Parameters 

      Nilsen, Erik T.; Freeman, Joshua; Grene, Ruth; Tokuhisa, James (Public Library of Science, 2014-12-22)
      The development of water stress resistant lines of commercial tomato by breeding or genetic engineering is possible, but will take considerable time before commercial varieties are available for production. However, grafting ...
    • Salting our freshwater lakes 

      Dugan, Hilary A.; Bartlett, Sarah L.; Burke, Samantha M.; Doubek, Jonathan P.; Krivak-Tetley, Flora E.; Skaff, Nicholas K.; Summers, Jamie C.; Farrell, Kaitlin J.; McCullough, Ian M.; Morales-Williams, Ana M.; Roberts, Derek C.; Ouyang, Zutao; Scordo, Facundo; Hanson, Paul C.; Weathers, Kathleen C. (NAS, 2017-03-08)
      The highest densities of lakes on Earth are in north temperate ecosystems, where increasing urbanization and associated chloride runoff can salinize freshwaters and threaten lake water quality and the many ecosystem services ...
    • Science and Values for a Finite Planet 

      Cairns, John (Asian Journal of Experimental Sciences, 2008)
      Exponential population growth on a finite planet means less resources per capita, and humankind is dependent upon the resources of the biospheric life support system for survival. However, humankind has acted, in the past, ...
    • Scientists, Time Management, and the Global Environmental Crisis 

      Cairns, John (Science and Society, 2006)
      The 21st century environmental crisis is vastly different from any other in human history. All the major components of the crisis are caused by humankind. With the largest human population ever on finite Earth, global ...
    • Searching for the physiological mechanism of density dependence: Does corticosterone regulate tadpole responses to density? 

      Belden, L. K.; Rubbo, M. J.; Wingfield, J. C.; Kiesecker, J. M. (University of Chicago Press, 2007-07)
      Density-dependent population regulation is important in many natural populations, and in those populations, high population density is a likely stressor. In amphibians, previous laboratory studies with tadpoles suggest ...
    • Seasonal controls on snow distribution and aerial ablation at the snow-patch and landscape scales, McMurdo Dry Valleys, Antarctica 

      Eveland, J. W.; Gooseff, M. N.; Lampkin, D. J.; Barrett, J. E.; Takacs-Vesbach, C. D. (Copernicus Publications, 2013)
      Accumulated snow in the McMurdo Dry Valleys, while limited, has great ecological significance to subnivian soil environments. Though sublimation dominates the ablation process in this region, measurable increases in soil ...
    • Second Generation Sequencing of the Mesothelioma Tumor Genome 

      Bueno, Raphael; De Rienzo, Assunta; Dong, Lingsheng; Gordon, Gavin J.; Hercus, Colin F.; Richards, William G.; Jensen, Roderick V.; Anwar, Arif; Maulik, Gautam; Chirieac, Lucian R.; Ho, Kim-Fong; Taillon, Bruce E.; Turcotte, Cynthia L.; Hercus, Robert G.; Gullans, Steven R.; Sugarbaker, David J. (PLOS, 2010-05-13)
      The current paradigm for elucidating the molecular etiology of cancers relies on the interrogation of small numbers of genes, which limits the scope of investigation. Emerging second-generation massively parallel DNA ...
    • Secondary structure in the target as a confounding factor in synthetic oligomer microarray design 

      Ratushna, Vladyslava G; Weller, Jennifer W; Gibas, Cynthia J (2005-03-08)
      Background Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes. It is frequently assumed that eliminating self-complementarity, ...