Now showing items 1-3 of 3

    • The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation 

      Ferrezuelo, Francisco; Colomina, Neus; Palmisano, Alida; Gari, Eloi; Gallego, Carme; Csikasz-Nagy, Attila; Aldea, Marti (Springer Nature, 2012-08)
      Budding yeast cells are assumed to trigger Start and enter the cell cycle only after they attain a critical size set by external conditions. However, arguing against deterministic models of cell size control, cell volume ...
    • JigCell Run Manager (JC-RM): a tool for managing large sets of biochemical model parametrizations 

      Palmisano, Alida; Hoops, Stefan; Watson, Layne T.; Jones, Thomas C.; Tyson, John J.; Shaffer, Clifford A. (Biomed Central Ltd, 2015-12-24)
      Background Most biomolecular reaction modeling tools allow users to build models with a single list of parameter values. However, a common scenario involves different parameterizations of the model to account for the ...
    • Multistate Model Builder (MSMB): a flexible editor for compact biochemical models 

      Palmisano, Alida; Hoops, Stefan; Watson, Layne T.; Jones, Thomas C, Jr.; Tyson, John J.; Shaffer, Clifford A. (Biomed Central Ltd, 2014-04-04)
      Background Building models of molecular regulatory networks is challenging not just because of the intrinsic difficulty of describing complex biological processes. Writing a model is a creative effort that calls for more ...