Now showing items 1-4 of 4
Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma
(Springer Nature, 2018-01-19)
Glioma is a unique neoplastic disease that develops exclusively in the central nervous system (CNS) and rarely metastasizes to other tissues. This feature strongly implicates the tumor-host CNS microenvironment in gliomagenesis ...
Cell Cycle Model System for Advancing Cancer Biomarker Research
(Springer Nature, 2017-12-21)
Progress in understanding the complexity of a devastating disease such as cancer has underscored the need for developing comprehensive panels of molecular markers for early disease detection and precision medicine applications. ...
Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis
(Springer Nature, 2017-08-30)
Little is known regarding the epigenetic basis of atherosclerosis. Here we present the CD14+ blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis. The transcriptome signature includes ...
Age-related variations in the methylome associated with gene expression in human monocytes and T cells
(Springer Nature, 2014-11)
Age-related variations in DNA methylation have been reported; however, the functional relevance of these differentially methylated sites (age-dMS) are unclear. Here we report potentially functional age-dMS, defined as ...