Now showing items 1-5 of 5
Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells
Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the ...
Jaccard distance based weighted sparse representation for coarse-to-fine plant species recognition
Leaf based plant species recognition plays an important role in ecological protection, however its application to large and modern leaf databases has been a long-standing obstacle due to the computational cost and feasibility. ...
A Bayesian Analysis of Copy Number Variations in Array Comparative Genomic Hybridization Data
(OMICS International, 2015-09-25)
Array Comparative Genomic Hybridization (CGH) has been widely used for detecting genomic copy number variations (CNVs). The central goal of array CGH data analysis is to accurately detect homogeneous regions of log intensity ...
Performance evaluation of indel calling tools using real short-read data
(Biomed Central Ltd, 2015-08-19)
Background Insertion and deletion (indel), a common form of genetic variation, has been shown to cause or contribute to human genetic diseases and cancer. With the advance of next-generation sequencing technology, many ...
Vindel: a simple pipeline for checking indel redundancy
(Biomed Central Ltd, 2014-11-19)
Background With the advance of next generation sequencing (NGS) technologies, a large number of insertion and deletion (indel) variants have been identified in human populations. Despite much research into variant calling, ...