Search
Now showing items 1-10 of 31
Variation in Eimeria oocyst count and species composition in weanling beef heifers
(American Society of Parasitology, 2006-10)
Rectal fecal samples were collected daily on 10 consecutive days in November 2004 from I I weaned beef heifers to assess daily variation in fecal oocyst count and species composition. Subsequent samples were collected from ...
TALEN-Mediated Modification of the Bovine Genome for Large-Scale Production of Human Serum Albumin
(PLOS, 2014-02-21)
As an initial step towards creating genetically modified cattle as a biopharming source of recombinant human serum albumin (rHSA), we report modification of the bovine albumin (bA) locus by transcription activator-like ...
Comparison of the Effects of Interleukin-1 on Equine Articular Cartilage Explants and Cocultures of Osteochondral and Synovial Explants
(Frontiers, 2017-09-20)
Osteoarthritis (OA) is a ubiquitous disease affecting many horses. The disease causes chronic pain and decreased performance for patients and great cost to owners for diagnosis and treatment. The most common treatments ...
Horses experimentally infected with sarcocystis neurona develop altered immune responses in vitro
(American Society of Parasitology, 2008-10)
Equine protozoal myeloencephalitis (EPM) due to Sarcocystis neurona infection is I of the most common neurologic diseases in horses in the United States. The mechanisms by which most horses resist disease, as well as the ...
Immunopathologic effects associated with Sarcocystis neurona-infected interferon-gamma knockout mice
(American Society of Parasitology, 2003-10)
Interferon-gamma knockout (IFN-gamma KO) mice were infected with Sarcocystis neurona merozoites to characterize the immunopathology associated with infection. By day 14 postinfection (PI), mice developed splenomegaly and ...
Analysis of the antigenic determinants of the OspC protein of the Lyme disease spirochetes: Evidence that the C10 motif is not immunodominant or required to elicit bactericidal antibody responses
(2019-04-17)
As Ixodes ticks spread to new regions, the incidence of Lyme disease (LD) in companion animals and humans will increase. Preventive strategies for LD in canines center on vaccination and tick control (acaricides). Both ...
Frequency of off-targeting in genome edited pigs produced via direct injection of the CRISPR/Cas9 system into developing embryos
(2019-05-06)
Abstract
Background
The CRISPR/Cas9 system can effectively introduce site-specific modifications to the genome. The efficiency is high enough to induce targeted genome ...
Novel roles for scleraxis in regulating adult tenocyte function
(2018-08-07)
Abstract
Background
Tendinopathies are common and difficult to resolve due to the formation of scar tissue that reduces the mechanical integrity of the tissue, leading to ...