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Antibody Responses during Hepatitis B Viral Infection
Hepatitis B is a DNA virus that infects liver cells and can cause both acute and chronic disease. It is believed that both viral and host factors are responsible for determining whether the infection is cleared or becomes ...
Multiscale Coupling of Transcranial Direct Current Stimulation to Neuron Electrodynamics: Modeling the Influence of the Transcranial Electric Field on Neuronal Depolarization
(Hindawi Publishing Corporation, 2014-10-23)
Transcranial direct current stimulation (tDCS) continues to demonstrate success as a medical intervention for neurodegenerative diseases, psychological conditions, and traumatic brain injury recovery. One aspect of tDCS ...
Multistate Model Builder (MSMB): a flexible editor for compact biochemical models
(Biomed Central Ltd, 2014-04-04)
Background Building models of molecular regulatory networks is challenging not just because of the intrinsic difficulty of describing complex biological processes. Writing a model is a creative effort that calls for more ...
Quantitative prediction of the effect of genetic variation using hidden Markov models
Background With the development of sequencing technologies, more and more sequence variants are available for investigation. Different classes of variants in the human genome have been identified, including single nucleotide ...