Now showing items 1-10 of 43
Modeling the Mechanisms by Which HIV Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa
Human immunodeficiency virus (HIV)-infected patients are at an increased risk of co-infection with human papilloma virus (HPV), and subsequent malignancies such as oral cancer. To determine the role of HIV-associated immune ...
Antibody Responses during Hepatitis B Viral Infection
Hepatitis B is a DNA virus that infects liver cells and can cause both acute and chronic disease. It is believed that both viral and host factors are responsible for determining whether the infection is cleared or becomes ...
Modeling stochasticity and variability in gene regulatory networks
Modeling stochasticity in gene regulatory networks is an important and complex problem in molecular systems biology. To elucidate intrinsic noise, several modeling strategies such as the Gillespie algorithm have been used ...
ADAM: Analysis of Discrete Models of Biological Systems Using Computer Algebra
Background Many biological systems are modeled qualitatively with discrete models, such as probabilistic Boolean networks, logical models, Petri nets, and agent-based models, to gain a better understanding of them. The ...
Disrupting Mosquito Reproduction and Parasite Development for Malaria Control
The control of mosquito populations with insecticide treated bed nets and indoor residual sprays remains the cornerstone of malaria reduction and elimination programs. In light of widespread insecticide resistance in ...
Linking neuronal brain activity to the glucose metabolism
Background Energy homeostasis ensures the functionality of the entire organism. The human brain as a missing link in the global regulation of the complex whole body energy metabolism is subject to recent investigation. The ...
An introduction to compartmental modeling for the budding infectious disease modeler
(Taylor & Francis, 2018-08-16)
Mathematical models are ubiquitous in the study of the transmission dynamics of infectious diseases, In particular, the classic ‘susceptible-infectious-recovered’ (SIR) paradigm provides a modeling framework that can be ...
Inexact solves in interpolatory model reduction
(Elsevier Science Inc, 2012-04-15)
Interpolatory weighted-H-2 model reduction
(Pergamon-Elsevier Science Ltd, 2013-05-01)