Browsing Scholarly Works, Department of Chemical Engineering by Title
Now showing items 44-63 of 106
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Identifying Human Interactors of SARS-CoV-2 Proteins and Drug Targets for COVID-19 using Network-Based Label Propagation
(Virginia Tech, 2020-06-22)Motivated by the critical need to identify new treatments for COVID- 19, we present a genome-scale, systems-level computational approach to prioritize drug targets based on their potential to regulate host- virus interactions ... -
Immunomagnetic separation of tumor initiating cells by screening two surface markers
(Springer Nature, 2017-01-11)Isolating tumor initiating cells (TICs) often requires screening of multiple surface markers, sometimes with opposite preferences. This creates a challenge for using bead-based immunomagnetic separation (IMS) that typically ... -
Impact of surface topography on biofilm formation by Candida albicans
(PLOS, 2018-06-18)Candida albicans is a fungal pathogen that causes serious biofilm-based infections. Here we have asked whether surface topography may affect C. albicans biofilm formation. We tested biofilm growth of the prototypical ... -
Impact of the Mode of Extraction on the Lipidomic Profile of Oils Obtained from Selected Amazonian Fruits
(MDPI, 2019-08-01)Oils and fats are important raw materials in food products, animal feed, cosmetics, and pharmaceuticals among others. The market today is dominated by oils derive, d from African palm, soybean, oilseed and animal fats. ... -
In Situ Control of Gas Flow by Modification of Gas-Solid Interactions
(American Physical Society, 2013-10-25)The boundary condition for gas flow at the solid-gas interface can be altered by in situ control of the state of a thin film adsorbed to the solid. A monolayer of ocatadecyltrichlorosilane (OTS) reversibly undergoes a ... -
The influence of interface bonding on thermal transport through solid-liquid interfaces
(AIP Publishing, 2013-06-01)We use time-domain thermoreflectance to show that interface thermal conductance, G, is proportional to the thermodynamic work of adhesion between gold and water, W-SL, for a series of five alkane-thiol monolayers at the ... -
Influence Of Molecular Weight Distribution on The Melt Extrusion Of High Density Polyethylene (HDPE): Effects Of Melt Relaxation Behavior on Morphology And Orientation in HDPE Extruded Tubular Films
(AIP Publishing, 1996-11-01)The influence of molecular weight distribution and extrusion processing variables on the morphological features and orientation of high density polyethylene (HDPE) uniaxially extruded tubular films was investigated. In ... -
Initial Results of a Flow Birefringence Study of the Hole Pressure for Polymer Melts
(AIP Publishing, 1984)The initial results of this study on a polymer melt shows that, for the present experimental conditions, stress field asymmetry has a negligible effect on the validity of the HP theory and that the theory may be extended ... -
Investigation into Polyurethane at Varying Dose Rates of Ionizing Radiation for Clinical Application
(Hindawi, 2018-10-01)Polyurethanes (PUs) are commonly used materials for medical devices. These devices are exposed repeatedly to radiation when patients undergo radiotherapy treatments. It has been found that peripherally inserted central ... -
Life Cycle Costs and Life Cycle Assessment for the Harvesting, Conversion, and the Use of Switchgrass to Produce Electricity
(Hindawi, 2013-09-23)This paper considers both LCA and LCC of the pyrolysis of switchgrass to use as an energy source in a conventional power plant. The process consists of cultivation, harvesting, transportation, storage, pyrolysis, transportation, ... -
Living Ring-Opening Polymerization of O-Carboxyanhydrides: The Search for Catalysts
(Frontiers Media, 2018-12-21)Biodegradable poly(a-hydroxy acids) can be synthesized by means of ring-opening polymerization (ROP) of O-carboxyanhydrides (OCAs). Numerous catalysts have been developed to control the living polymerization of OCAs. Here ... -
Low-input and multiplexed microfluidic assay reveals epigenomic variation across cerebellum and prefrontal cortex
(AAAS, 2018-04-18)Extensive effort is under way to survey the epigenomic landscape of primary ex vivo tissues to establish normal reference data and to discern variation associated with disease. The low abundance of some tissue types and ... -
Lubrication forces in air and accommodation coefficient measured by a thermal damping method using an atomic force microscope
(American Physical Society, 2010-05-01)By analysis of the thermally driven oscillation of an atomic force microscope (AFM) cantilever, we have measured both the damping and static forces acting on a sphere near a flat plate immersed in gas. By varying the ... -
A membrane with ion fluxes responsive to temperature, pH and voltage
(2019-05-15)Cell membranes of biological cells embedded with nuclear pore complexes (NPCs) are capable of controlling the flow of ions, e.g. Na+, K+ and Ca2+ by responding to stimuli, e.g. pH and voltage. From the inspiration of NPCs, ... -
Methanol decomposition on single-crystal cu2o
(American Institute of Physics, 1990-05-01)CH3OD decomposition has been studied over the stoichiometric, nonpolar (111) and polar, copper_terminated (100) surfaces of Cu2O. Thermal desorption studies for monolayer coverages of methanol at 90 ... -
Microfluidic Electroporation for Cellular Analysis and Delivery
(The Royal Society of Chemistry, 2013-07-08)Electroporation is a simple yet powerful technique for breaching the cell membrane barrier. The applications of electroporation can be generally divided into two categories: the release of intracellular proteins, nucleic ... -
Microfluidic systems and methods for chromatin immunoprecipitation (ChIP)
(United States Patent and Trademark Office, 2017-08-15)An integrated microfluidic chromatin immunoprecipitation assay dramatically improves the collection efficiency of ChIP DNA from cells. Immunoprecipitation of chromatin fragments is conducted in a microfluidic chamber with ... -
Microfluidics for genome-wide studies involving next generation sequencing
(AIP Publishing, 2017-03-10)Next-generation sequencing (NGS) has revolutionized how molecular biology studies are conducted. Its decreasing cost and increasing throughput permit profiling of genomic, transcriptomic, and epigenomic features for a wide ... -
Mitigation of bidirectional solute flux in forward osmosis via membrane surface coating of zwitterion functionalized carbon nanotubes
(Elsevier, 2019-07-08)Forward osmosis (FO) has emerged as a promising membrane technology to yield high-quality reusable water from various water sources. A key challenge to be solved is the bidirectional solute flux (BSF), including reverse ... -
Modeling iontophoretic drug delivery in a microfluidic device
(2020-09-21)Iontophoresis employs low-intensity electrical voltage and continuous constant current to direct a charged drug into a tissue. Iontophoretic drug delivery has recently been used as a novel method for cancer treatment in ...
